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    MBD10 methyl-CPG-binding domain 10 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 838103, updated on 18-Sep-2024

    Summary

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    Official Symbol
    MBD10
    Official Full Name
    methyl-CPG-binding domain 10
    Primary source
    TAIR:AT1G15340
    Locus tag
    AT1G15340
    See related
    Araport:AT1G15340
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F9L1.28; F9L1_28; methyl-CPG-binding domain 10
    Summary
    Protein containing methyl-CpG-binding domain.Has sequence similarity to human MBD proteins.
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    Genomic context

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    See MBD10 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    2
    Sequence:
    Chromosome: 1; NC_003070.9 (5275616..5277869, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene seed dormancy control protein Neighboring gene Cystathionine beta-synthase (CBS) protein Neighboring gene DUF4050 family protein Neighboring gene miscRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Group C MAP kinases phosphorylate MBD10 to regulate ABA-induced leaf senescence in Arabidopsis. Li Y, et al. Plant J, 2024 Jun. PMID 38477703
    2. Multimegabase silencing in nucleolar dominance involves siRNA-directed DNA methylation and specific methylcytosine-binding proteins. Preuss SB, et al. Mol Cell, 2008 Dec 5. PMID 19061642, Free PMC Article
    3. Characterization of Arabidopsis thaliana methyl-CpG-binding domain (MBD) proteins. Zemach A, et al. Plant J, 2003 Jun. PMID 12787239
    4. A proteomic strategy for global analysis of plant protein complexes. Aryal UK, et al. Plant Cell, 2014 Oct. PMID 25293756, Free PMC Article
    5. CrY2H-seq: a massively multiplexed assay for deep-coverage interactome mapping. Wanamaker SA, et al. Nat Methods, 2017 Aug. PMID 28650476, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Group C MAP kinases phosphorylate MBD10 to regulate ABA-induced leaf senescence in Arabidopsis.
      Title: Group C MAP kinases phosphorylate MBD10 to regulate ABA-induced leaf senescence in Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001198074.1
    NM_101403.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables methyl-CpG binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol HDA PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    methyl-CPG-binding domain 10
    NP_001185003.1
    • methyl-CPG-binding domain 10 (MBD10); FUNCTIONS IN: methyl-CpG binding, DNA binding; INVOLVED IN: biological_process unknown; LOCATED IN: nucleus; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: DNA-binding, integrase-type (InterPro:IPR016177), Methyl-CpG DNA binding (InterPro:IPR001739); BEST Arabidopsis thaliana protein match is: methyl-CPG-binding domain 11 (TAIR:AT3G15790.1).
    NP_563971.1
    • methyl-CPG-binding domain 10 (MBD10); FUNCTIONS IN: methyl-CpG binding, DNA binding; INVOLVED IN: biological_process unknown; LOCATED IN: nucleus; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: DNA-binding, integrase-type (InterPro:IPR016177), Methyl-CpG DNA binding (InterPro:IPR001739); BEST Arabidopsis thaliana protein match is: methyl-CPG-binding domain 11 (TAIR:AT3G15790.1); Has 137026 Blast hits to 72034 proteins in 3183 species: Archae - 674; Bacteria - 27556; Metazoa - 48373; Fungi - 14456; Plants - 6804; Viruses - 747; Other Eukaryotes - 38416 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      5275616..5277869 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_101403.4 → NP_563971.1  methyl-CPG-binding domain 10 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_563971.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0WLE9, Q9XI36
      UniProtKB/TrEMBL
      A0A178W7K9, A0A5S9UI19
      Conserved Domains (2) summary
      TIGR00927
      Location:152 → 329
      2A1904; K+-dependent Na+/Ca+ exchanger
      pfam01429
      Location:4 → 77
      MBD; Methyl-CpG binding domain

    2. NM_001198074.1 → NP_001185003.1  methyl-CPG-binding domain 10 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001185003.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9UI19
      Conserved Domains (1) summary
      pfam01429
      Location:8 → 56
      MBD; Methyl-CpG binding domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9XI36.1

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