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    IAR1 ZIP metal ion transporter family [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 843138, updated on 18-Sep-2024

    Summary

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    Official Symbol
    IAR1
    Official Full Name
    ZIP metal ion transporter family
    Primary source
    TAIR:AT1G68100
    Locus tag
    AT1G68100
    See related
    Araport:AT1G68100
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    IAA-ALANINE RESISTANCE PROTEIN 1; IAA-ALANINE RESISTANT 1; T23K23.5; T23K23_5
    Summary
    member of IAA-alanine resistance protein 1
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    Genomic context

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    See IAR1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    11
    Sequence:
    Chromosome: 1; NC_003070.9 (25521100..25524250)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Zinc finger, C3HC4 type (RING finger) family protein Neighboring gene 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily protein Neighboring gene annexin 5 Neighboring gene ENTH/ANTH/VHS superfamily protein Neighboring gene BASIC PENTACYSTEINE protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. AtIAR1 is a Zn transporter that regulates auxin metabolism in Arabidopsis thaliana. Gate T, et al. J Exp Bot, 2024 Feb 28. PMID 37988591, Free PMC Article
    2. Compensatory mutations in predicted metal transporters modulate auxin conjugate responsiveness in Arabidopsis. Rampey RA, et al. G3 (Bethesda), 2013 Jan. PMID 23316445, Free PMC Article
    3. Tandem affinity purification and mass spectrometric analysis of ubiquitylated proteins in Arabidopsis. Saracco SA, et al. Plant J, 2009 Jul. PMID 19292762, Free PMC Article
    4. Putative glycosyltransferases and other plant Golgi apparatus proteins are revealed by LOPIT proteomics. Nikolovski N, et al. Plant Physiol, 2012 Oct. PMID 22923678, Free PMC Article
    5. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. MTP5 and IAR1 transport metals in an antagonistic fashion to regulate metal homeostasis.
      Title: Compensatory mutations in predicted metal transporters modulate auxin conjugate responsiveness in Arabidopsis.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001334346.1
    NM_105480.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables metal ion transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in metal ion transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in endoplasmic reticulum HDA PubMed 
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    ZIP metal ion transporter family
    NP_564921.1
    • IAA-ALANINE RESISTANT 1 (IAR1); FUNCTIONS IN: metal ion transmembrane transporter activity; INVOLVED IN: transmembrane transport, metal ion transport; LOCATED IN: endomembrane system, membrane; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Zinc/iron permease (InterPro:IPR003689); Has 3060 Blast hits to 2483 proteins in 472 species: Archae - 4; Bacteria - 929; Metazoa - 1358; Fungi - 209; Plants - 119; Viruses - 3; Other Eukaryotes - 438 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      25521100..25524250
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_105480.3 → NP_564921.1  ZIP metal ion transporter family [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_564921.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8H9F6, Q8VYF8, Q9C9X4, Q9M647
      UniProtKB/TrEMBL
      A0A178WG97, A0A5S9WSN7, A0A654ENL2
      Conserved Domains (1) summary
      pfam02535
      Location:105 → 461
      Zip; ZIP Zinc transporter

    2. NM_001334346.1 → NP_001322211.1  ZIP metal ion transporter family [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8ATB0, A0A5S9WSN7, A0A654ENL2
      Conserved Domains (1) summary
      pfam02535
      Location:105 → 428
      Zip; ZIP Zinc transporter
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9M647.3

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