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    Bend4 BEN domain containing 4 [ Mus musculus (house mouse) ]

    Gene ID: 666938, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Bend4provided by MGI
    Official Full Name
    BEN domain containing 4provided by MGI
    Primary source
    MGI:MGI:3648414
    See related
    Ensembl:ENSMUSG00000092060 AllianceGenome:MGI:3648414
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    EG666938; D330027G24Rik
    Summary
    Predicted to enable DNA binding activity. Orthologous to human BEND4 (BEN domain containing 4). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Broad expression in placenta adult (RPKM 6.3), testis adult (RPKM 2.9) and 15 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Bend4 in Genome Data Viewer
    Location:
    5 C3.1; 5 36.06 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (67549490..67585471, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (67392147..67428128, complement)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E3579 Neighboring gene STARR-seq mESC enhancer starr_13313 Neighboring gene transmembrane protein 33 Neighboring gene CRISPRi-validated cis-regulatory element for Bend4 and Slc30a9 Neighboring gene solute carrier family 30 (zinc transporter), member 9 Neighboring gene STARR-seq mESC enhancer starr_13315 Neighboring gene STARR-seq mESC enhancer starr_13316 Neighboring gene predicted gene, 33345 Neighboring gene predicted gene 42632 Neighboring gene RIKEN cDNA C330024D21 gene Neighboring gene CRISPRi-validated cis-regulatory element for Bend4 and Bendr Neighboring gene predicted gene, 40315 Neighboring gene 60S ribosomal protein L37 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Lineage-specific biology revealed by a finished genome assembly of the mouse. Church DM, et al. PLoS Biol, 2009 May 5. PMID 19468303, Free PMC Article
    2. ACAA2 is a ligand-dependent coactivator for thyroid hormone receptor β1. Wang W, et al. Biochem Biophys Res Commun, 2021 Oct 22. PMID 34474245, Free PMC Article
    3. A germline-specific class of small RNAs binds mammalian Piwi proteins. Girard A, et al. Nature, 2006 Jul 13. PMID 16751776
    4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    BEN domain-containing protein 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001164806.1 → NP_001158278.1  BEN domain-containing protein 4

      See identical proteins and their annotated locations for NP_001158278.1

      Status: VALIDATED

      Source sequence(s)
      AC122562
      Consensus CDS
      CCDS51512.1
      UniProtKB/Swiss-Prot
      P86174
      Related
      ENSMUSP00000132684.2, ENSMUST00000169190.5
      Conserved Domains (2) summary
      smart00338
      Location:334 → 371
      BRLZ; basic region leucin zipper
      smart01025
      Location:420 → 498
      BEN; The BEN domain is found in diverse animal proteins

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      67549490..67585471 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006504059.4 → XP_006504122.1  BEN domain-containing protein 4 isoform X2

      UniProtKB/TrEMBL
      A0A0J9YV05
      Conserved Domains (1) summary
      cl21462
      Location:334 → 371
      bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain

    2. XM_030254766.1 → XP_030110626.1  BEN domain-containing protein 4 isoform X1

      UniProtKB/Swiss-Prot
      P86174
      Related
      ENSMUSP00000144639.2, ENSMUST00000201972.2
      Conserved Domains (2) summary
      smart00338
      Location:334 → 371
      BRLZ; basic region leucin zipper
      smart01025
      Location:420 → 498
      BEN; The BEN domain is found in diverse animal proteins
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P86174.2 GenPept UniProtKB/Swiss-Prot:P86174

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