Csdc2 cold shock domain containing C2, RNA binding [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Csdc2provided by MGI
Official Full Name: cold shock domain containing C2, RNA bindingprovided by MGI
Primary source: MGI:MGI:2146027
See related: Ensembl:ENSMUSG00000042109 AllianceGenome:MGI:2146027
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Pippin
Summary: Predicted to enable mRNA 3'-UTR binding activity. Predicted to be involved in regulation of mRNA stability. Predicted to be located in nucleus. Predicted to be active in cytoplasm. Is expressed in brain; ganglia; and neural retina. Orthologous to human CSDC2 (cold shock domain containing C2). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Broad expression in cerebellum adult (RPKM 66.3), frontal lobe adult (RPKM 63.2) and 15 other tissues See more
Orthologs: human all
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Genomic context

Location:: 15 E1; 15 38.28 cM

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	15	NC_000081.7 (81820960..81835142)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	15	NC_000081.6 (81936759..81950941)

Chromosome 15 - NC_000081.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

AI481750 (e-PCR)
- UniSTS:180800

RH126196 (e-PCR)
- UniSTS:162904

AI415250 (e-PCR)
- UniSTS:160486

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables RNA binding	ISO Inferred from Sequence Orthology more info
enables mRNA 3'-UTR binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in mRNA processing	IEA Inferred from Electronic Annotation more info
involved_in regulation of mRNA stability	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: cold shock domain-containing protein C2

Names: RNA-binding protein PIPPin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_145473.3 → NP_663448.2 cold shock domain-containing protein C2

See identical proteins and their annotated locations for NP_663448.2

Status: VALIDATED

Source sequence(s)

AC102103, AK028916, AK132493, BB871178, CO041050

Consensus CDS

CCDS27677.1

UniProtKB/Swiss-Prot

Q3V1F0, Q91YQ3

Related

ENSMUSP00000044441.8, ENSMUST00000038757.8

Conserved Domains (1) summary

cd04458
Location:71 → 135

CSP_CDS; Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea. CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box protein. ...