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    5'-3' exonuclease family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 838389, updated on 18-Sep-2024

    Summary

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    Official Full Name
    5'-3' exonuclease family protein
    Primary source
    TAIR:AT1G18090
    Locus tag
    AT1G18090
    See related
    Araport:AT1G18090
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    T10F20.10
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    11
    Sequence:
    Chromosome: 1; NC_003070.9 (6224405..6227822)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Transducin/WD40 repeat-like superfamily protein Neighboring gene PEBP (phosphatidylethanolamine-binding protein) family protein Neighboring gene ncRNA Neighboring gene miscRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    NM_101671.5
    NM_179353.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    5'-3' exonuclease family protein
    NP_564047.1
    • 5'-3' exonuclease family protein; FUNCTIONS IN: DNA binding, catalytic activity, nuclease activity; INVOLVED IN: DNA repair; LOCATED IN: cellular_component unknown; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: XPG conserved site (InterPro:IPR019974), XPG N-terminal (InterPro:IPR006085), DNA repair protein (XPGC)/yeast Rad (InterPro:IPR006084), 5'-3' exonuclease, C-terminal subdomain (InterPro:IPR020045), Helix-hairpin-helix motif, class 2 (InterPro:IPR008918), XPG/RAD2 endonuclease (InterPro:IPR006086); BEST Arabidopsis thaliana protein match is: 5'-3' exonuclease family protein (TAIR:AT1G29630.2); Has 2134 Blast hits to 2045 proteins in 397 species: Archae - 265; Bacteria - 69; Metazoa - 518; Fungi - 574; Plants - 189; Viruses - 16; Other Eukaryotes - 503 (source: NCBI BLink).
    NP_849684.1
    • 5'-3' exonuclease family protein; FUNCTIONS IN: DNA binding, catalytic activity, nuclease activity; INVOLVED IN: DNA repair; LOCATED IN: cellular_component unknown; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: XPG conserved site (InterPro:IPR019974), XPG N-terminal (InterPro:IPR006085), DNA repair protein (XPGC)/yeast Rad (InterPro:IPR006084), 5'-3' exonuclease, C-terminal subdomain (InterPro:IPR020045), Helix-hairpin-helix motif, class 2 (InterPro:IPR008918), XPG/RAD2 endonuclease (InterPro:IPR006086); BEST Arabidopsis thaliana protein match is: 5'-3' exonuclease family protein (TAIR:AT1G29630.2); Has 2139 Blast hits to 2052 proteins in 399 species: Archae - 267; Bacteria - 71; Metazoa - 522; Fungi - 572; Plants - 187; Viruses - 16; Other Eukaryotes - 504 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      6224405..6227822
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_101671.5 → NP_564047.1  5'-3' exonuclease family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_564047.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178W174, A0A654EBM3, A0A7G2DU39, Q94A33
      Conserved Domains (2) summary
      cd09901
      Location:223 → 295
      H3TH_FEN1-like; H3TH domains of Flap endonuclease-1 (FEN1)-like structure specific 5' nucleases: FEN1 (eukaryotic) and EXO1
      cd09857
      Location:1 → 207
      PIN_EXO1; PIN domain of Exonuclease-1, a structure-specific, divalent-metal-ion dependent, 5' nuclease and homologs

    2. NM_179353.2 → NP_849684.1  5'-3' exonuclease family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_849684.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9V119, A0A7G2DU39, F4IAM4
      Conserved Domains (2) summary
      cd09901
      Location:223 → 295
      H3TH_FEN1-like; H3TH domains of Flap endonuclease-1 (FEN1)-like structure specific 5' nucleases: FEN1 (eukaryotic) and EXO1
      cd09857
      Location:1 → 209
      PIN_EXO1; FEN-like PIN domains of Exonuclease-1, a structure-specific, divalent-metal-ion dependent, 5' nuclease and homologs
    Nucleotide Protein
    Heading Accession and Version

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