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    Dpf1 double PHD fingers 1 [ Mus musculus (house mouse) ]

    Gene ID: 29861, updated on 3-Dec-2024

    Summary

    Official Symbol
    Dpf1provided by MGI
    Official Full Name
    double PHD fingers 1provided by MGI
    Primary source
    MGI:MGI:1352748
    See related
    Ensembl:ENSMUSG00000030584 AllianceGenome:MGI:1352748
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Neud4
    Summary
    Predicted to enable sequence-specific double-stranded DNA binding activity. Involved in nervous system development. Part of nBAF complex. Is expressed in several structures, including eye; genitourinary system; limb; nervous system; and submandibular gland. Orthologous to human DPF1 (double PHD fingers 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in CNS E18 (RPKM 15.1), CNS E14 (RPKM 15.0) and 8 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Dpf1 in Genome Data Viewer
    Location:
    7 B1; 7 16.94 cM
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (29003366..29017017)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (29303952..29317592)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 45977 Neighboring gene protein phosphatase 1, regulatory inhibitor subunit 14A Neighboring gene STARR-seq mESC enhancer starr_18467 Neighboring gene signal-induced proliferation-associated 1 like 3 Neighboring gene STARR-seq mESC enhancer starr_18469 Neighboring gene STARR-seq mESC enhancer starr_18470 Neighboring gene STARR-seq mESC enhancer starr_18474 Neighboring gene STARR-seq mESC enhancer starr_18476 Neighboring gene RIKEN cDNA 4932431P20 gene Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:30303585-30303694 Neighboring gene predicted gene, 38982

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Chemically induced (ENU) (1) 
    • Endonuclease-mediated (1) 
    • Targeted (3) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables sequence-specific double-stranded DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in chromatin NAS
    Non-traceable Author Statement
    more info
    PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    part_of nBAF complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of nBAF complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of nBAF complex NAS
    Non-traceable Author Statement
    more info
    PubMed 
    located_in nucleoplasm TAS
    Traceable Author Statement
    more info
     

    General protein information

    Preferred Names
    zinc finger protein neuro-d4
    Names
    BAF45B
    BRG1-associated factor 45B
    D4, zinc and double PHD fingers family 1
    neuro-d4
    neuronal d4 domain family member

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001368371.2NP_001355300.1  zinc finger protein neuro-d4 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC166079
      Consensus CDS
      CCDS90198.1
      UniProtKB/Swiss-Prot
      Q9QX65, Q9QX66, Q9QYA4
      UniProtKB/TrEMBL
      D3YYG6
      Related
      ENSMUSP00000070539.6, ENSMUST00000065181.12
    2. NM_001403205.1NP_001390134.1  zinc finger protein neuro-d4 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC166079
      UniProtKB/TrEMBL
      D3YY44, D3YYG6
      Related
      ENSMUSP00000103866.2, ENSMUST00000108231.8
    3. NM_001403206.1NP_001390135.1  zinc finger protein neuro-d4 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC166079
      UniProtKB/TrEMBL
      D3YYG6
      Related
      ENSMUSP00000103865.2, ENSMUST00000108230.8
    4. NM_001403207.1NP_001390136.1  zinc finger protein neuro-d4 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC166079
      UniProtKB/TrEMBL
      D3YYG6
    5. NM_001403208.1NP_001390137.1  zinc finger protein neuro-d4 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC166079
      UniProtKB/TrEMBL
      D3YYG6
    6. NM_001403209.1NP_001390138.1  zinc finger protein neuro-d4 isoform 7

      Status: VALIDATED

      Source sequence(s)
      AC166079
      UniProtKB/TrEMBL
      D3YYG6
    7. NM_001403210.1NP_001390139.1  zinc finger protein neuro-d4 isoform 8

      Status: VALIDATED

      Source sequence(s)
      AC166079
      UniProtKB/TrEMBL
      D3YYG6
    8. NM_001403211.1NP_001390140.1  zinc finger protein neuro-d4 isoform 9

      Status: VALIDATED

      Source sequence(s)
      AC166079
      UniProtKB/TrEMBL
      D3YYG6
    9. NM_001403212.1NP_001390141.1  zinc finger protein neuro-d4 isoform 10

      Status: VALIDATED

      Source sequence(s)
      AC166079
      UniProtKB/TrEMBL
      D3YYG6
    10. NM_001403214.1NP_001390143.1  zinc finger protein neuro-d4 isoform 11

      Status: VALIDATED

      Source sequence(s)
      AC166079
      UniProtKB/TrEMBL
      D3YYG6
    11. NM_001403215.1NP_001390144.1  zinc finger protein neuro-d4 isoform 12

      Status: VALIDATED

      Source sequence(s)
      AC166079
      UniProtKB/TrEMBL
      D3YYG6
    12. NM_001403216.1NP_001390145.1  zinc finger protein neuro-d4 isoform 13

      Status: VALIDATED

      Source sequence(s)
      AC166079
      UniProtKB/TrEMBL
      D3YYG6
    13. NM_001403217.1NP_001390146.1  zinc finger protein neuro-d4 isoform 14

      Status: VALIDATED

      Source sequence(s)
      AC166079
    14. NM_001403218.1NP_001390147.1  zinc finger protein neuro-d4 isoform 15

      Status: VALIDATED

      Source sequence(s)
      AC166079
    15. NM_001403219.1NP_001390148.1  zinc finger protein neuro-d4 isoform 16

      Status: VALIDATED

      Source sequence(s)
      AC166079
      UniProtKB/TrEMBL
      D3YYG6
    16. NM_001403220.1NP_001390149.1  zinc finger protein neuro-d4 isoform 16

      Status: VALIDATED

      Source sequence(s)
      AC166079
      UniProtKB/TrEMBL
      D3YYG6
    17. NM_013874.3NP_038902.1  zinc finger protein neuro-d4 isoform 1

      See identical proteins and their annotated locations for NP_038902.1

      Status: VALIDATED

      Source sequence(s)
      AC166079
      Consensus CDS
      CCDS21071.1
      UniProtKB/TrEMBL
      D3YYG6, Q6GTK4
      Related
      ENSMUSP00000054385.7, ENSMUST00000049977.13
      Conserved Domains (4) summary
      COG5189
      Location:186220
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      cd15530
      Location:328373
      PHD2_d4; PHD finger 2 found in d4 gene family proteins
      cd15690
      Location:270327
      PHD1_DPF1; PHD finger 1 found in D4, zinc and double PHD fingers family 1 (DPF1)
      pfam14051
      Location:1384
      Requiem_N; N-terminal domain of DPF2/REQ

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      29003366..29017017
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030242655.2XP_030098515.1  zinc finger protein neuro-d4 isoform X4

      UniProtKB/TrEMBL
      D3YYG6
      Conserved Domains (4) summary
      COG5189
      Location:225259
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      cd15530
      Location:350405
      PHD2_d4; PHD finger 2 found in d4 gene family proteins
      cd15690
      Location:292349
      PHD1_DPF1; PHD finger 1 found in D4, zinc and double PHD fingers family 1 (DPF1)
      pfam14051
      Location:52123
      Requiem_N; N-terminal domain of DPF2/REQ
    2. XM_036153156.1XP_036009049.1  zinc finger protein neuro-d4 isoform X8

      Conserved Domains (4) summary
      COG5189
      Location:195229
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      cd15530
      Location:337392
      PHD2_d4; PHD finger 2 found in d4 gene family proteins
      cd15690
      Location:279336
      PHD1_DPF1; PHD finger 1 found in D4, zinc and double PHD fingers family 1 (DPF1)
      pfam14051
      Location:52118
      Requiem_N; N-terminal domain of DPF2/REQ
    3. XM_030242657.2XP_030098517.1  zinc finger protein neuro-d4 isoform X7

      UniProtKB/TrEMBL
      D3YYG6
      Conserved Domains (4) summary
      COG5189
      Location:212246
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      cd15530
      Location:337392
      PHD2_d4; PHD finger 2 found in d4 gene family proteins
      cd15690
      Location:279336
      PHD1_DPF1; PHD finger 1 found in D4, zinc and double PHD fingers family 1 (DPF1)
      pfam14051
      Location:39110
      Requiem_N; N-terminal domain of DPF2/REQ
    4. XM_036153157.1XP_036009050.1  zinc finger protein neuro-d4 isoform X12

      UniProtKB/TrEMBL
      D3YYG6
      Conserved Domains (4) summary
      COG5189
      Location:182216
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      cd15530
      Location:324379
      PHD2_d4; PHD finger 2 found in d4 gene family proteins
      cd15690
      Location:266323
      PHD1_DPF1; PHD finger 1 found in D4, zinc and double PHD fingers family 1 (DPF1)
      pfam14051
      Location:39105
      Requiem_N; N-terminal domain of DPF2/REQ
    5. XM_036153160.1XP_036009053.1  zinc finger protein neuro-d4 isoform X18

      UniProtKB/TrEMBL
      D3YYG6
      Conserved Domains (4) summary
      COG5189
      Location:156190
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      cd15530
      Location:298353
      PHD2_d4; PHD finger 2 found in d4 gene family proteins
      cd15690
      Location:240297
      PHD1_DPF1; PHD finger 1 found in D4, zinc and double PHD fingers family 1 (DPF1)
      pfam14051
      Location:1379
      Requiem_N; N-terminal domain of DPF2/REQ
    6. XM_030242653.2XP_030098513.2  zinc finger protein neuro-d4 isoform X9

      UniProtKB/TrEMBL
      D3YYG6
      Conserved Domains (4) summary
      COG5189
      Location:186220
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      cd15530
      Location:328383
      PHD2_d4; PHD finger 2 found in d4 gene family proteins
      cd15690
      Location:270327
      PHD1_DPF1; PHD finger 1 found in D4, zinc and double PHD fingers family 1 (DPF1)
      pfam14051
      Location:1379
      Requiem_N; N-terminal domain of DPF2/REQ
    7. XM_036153159.1XP_036009052.1  zinc finger protein neuro-d4 isoform X16

      UniProtKB/TrEMBL
      D3YYG6
      Conserved Domains (4) summary
      COG5189
      Location:186220
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      cd15530
      Location:311366
      PHD2_d4; PHD finger 2 found in d4 gene family proteins
      cd15690
      Location:253310
      PHD1_DPF1; PHD finger 1 found in D4, zinc and double PHD fingers family 1 (DPF1)
      pfam14051
      Location:1379
      Requiem_N; N-terminal domain of DPF2/REQ
    8. XM_036153158.1XP_036009051.1  zinc finger protein neuro-d4 isoform X14

      UniProtKB/TrEMBL
      D3YYG6
      Conserved Domains (4) summary
      COG5189
      Location:186220
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      cd15530
      Location:328373
      PHD2_d4; PHD finger 2 found in d4 gene family proteins
      cd15690
      Location:270327
      PHD1_DPF1; PHD finger 1 found in D4, zinc and double PHD fingers family 1 (DPF1)
      pfam14051
      Location:1379
      Requiem_N; N-terminal domain of DPF2/REQ
    9. XM_006540039.4XP_006540102.1  zinc finger protein neuro-d4 isoform X13

      UniProtKB/TrEMBL
      D3YYG6
      Conserved Domains (4) summary
      COG5189
      Location:178212
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      cd15530
      Location:320375
      PHD2_d4; PHD finger 2 found in d4 gene family proteins
      cd15690
      Location:262319
      PHD1_DPF1; PHD finger 1 found in D4, zinc and double PHD fingers family 1 (DPF1)
      pfam14051
      Location:576
      Requiem_N; N-terminal domain of DPF2/REQ