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    Fpr3 formyl peptide receptor 3 [ Mus musculus (house mouse) ]

    Gene ID: 14294, updated on 9-Dec-2024

    Summary

    Official Symbol
    Fpr3provided by MGI
    Official Full Name
    formyl peptide receptor 3provided by MGI
    Primary source
    MGI:MGI:1194495
    See related
    Ensembl:ENSMUSG00000079700 AllianceGenome:MGI:1194495
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    ALX; Fprl1; Lxa4r; Fpr-s1; LXA4-R; Fpr-rs1
    Summary
    Enables signaling receptor activity. Acts upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in cytoplasm. Predicted to be active in plasma membrane. Orthologous to several human genes including FPR2 (formyl peptide receptor 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See Fpr3 in Genome Data Viewer
    Location:
    17 A3.2; 17 10.66 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (18190720..18191939)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (17970458..17971677)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene mitochondrial ribosomal protein L41 pseudogene Neighboring gene non-SMC condensin II complex, subunit H2 pseudogene Neighboring gene formyl peptide receptor 2 pseudogene Neighboring gene STARR-seq mESC enhancer starr_41969 Neighboring gene STARR-seq mESC enhancer starr_41970 Neighboring gene formyl peptide receptor, related sequence 5 Neighboring gene formyl peptide receptor, related sequence 4

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables N-formyl peptide receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables RAGE receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables amyloid-beta binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables complement receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables scavenger receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables signaling receptor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables signaling receptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    formyl peptide receptor-related sequence 1
    Names
    FMLP-R-I
    FMLP-related receptor I
    LXA4 receptor
    N-formyl peptide receptor 2
    N-formyl peptide receptor 3
    N-formylpeptide receptor-like 1
    formyl peptide receptor-like 1
    lipoxin A4 receptor

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_008042.2NP_032068.2  formyl peptide receptor-related sequence 1

      See identical proteins and their annotated locations for NP_032068.2

      Status: VALIDATED

      Source sequence(s)
      AC171405
      Consensus CDS
      CCDS28420.1
      UniProtKB/Swiss-Prot
      O08790, O88535
      Related
      ENSMUSP00000111227.2, ENSMUST00000115565.2
      Conserved Domains (1) summary
      pfam00001
      Location:43302
      7tm_1; 7 transmembrane receptor (rhodopsin family)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      18190720..18191939
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)