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    Or4p21 olfactory receptor family 4 subfamily P member 21 [ Mus musculus (house mouse) ]

    Gene ID: 258167, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Or4p21provided by MGI
    Official Full Name
    olfactory receptor family 4 subfamily P member 21provided by MGI
    Primary source
    MGI:MGI:3031370
    See related
    Ensembl:ENSMUSG00000090097 AllianceGenome:MGI:3031370
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm13757; Olfr1182; MOR225-7P; MOR225-8P; Olfr1536-ps1
    Summary
    Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
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    Genomic context

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    See Or4p21 in Genome Data Viewer
    Location:
    2 D; 2 49.98 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (88276363..88279465, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (88446019..88449121, complement)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 4 subfamily P member 19 Neighboring gene olfactory receptor family 4 subfamily P member 20 Neighboring gene STARR-seq mESC enhancer starr_05064 Neighboring gene olfactory receptor family 4 subfamily C member 31 Neighboring gene STARR-seq mESC enhancer starr_05065 Neighboring gene olfactory receptor family 4 subfamily P member 22

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of potential regulatory motifs in odorant receptor genes by analysis of promoter sequences. Michaloski JS, et al. Genome Res, 2006 Sep. PMID 16902085, Free PMC Article
    2. Odorant and vomeronasal receptor genes in two mouse genome assemblies. Zhang X, et al. Genomics, 2004 May. PMID 15081110
    3. The olfactory receptor gene superfamily of the mouse. Zhang X, et al. Nat Neurosci, 2002 Feb. PMID 11802173
    4. Different evolutionary processes shaped the mouse and human olfactory receptor gene families. Young JM, et al. Hum Mol Genet, 2002 Mar 1. PMID 11875048
    5. Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels. Young JM, et al. Genome Biol, 2003. PMID 14611657, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables olfactory receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    olfactory receptor 1182
    Names
    GA_x6K02T2Q125-49934557-49933640
    MOR225-16_p
    olfactory receptor 1536, pseudogene 1
    olfactory receptor MOR225-7P
    olfactory receptor MOR225-8P

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001011535.2 → NP_001011535.1  olfactory receptor 1182

      See identical proteins and their annotated locations for NP_001011535.1

      Status: VALIDATED

      Source sequence(s)
      AL928912, DR065631
      Consensus CDS
      CCDS16336.1
      UniProtKB/TrEMBL
      Q7TR17
      Related
      ENSMUSP00000136580.2, ENSMUST00000179450.9
      Conserved Domains (2) summary
      pfam00001
      Location:39 → 285
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:29 → 302
      7tm_4; Olfactory receptor

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      88276363..88279465 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NG_001948.1: Suppressed sequence

      Description
      NG_001948.1: This RefSeq was permanently suppressed because it is now thought that this gene does encode a protein.
    Nucleotide Protein Strain
    Heading Accession and Version

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