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    UPL7 ubiquitin-protein ligase 7 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 824475, updated on 18-Sep-2024

    Summary

    Official Symbol
    UPL7
    Official Full Name
    ubiquitin-protein ligase 7
    Primary source
    TAIR:AT3G53090
    Locus tag
    AT3G53090
    See related
    Araport:AT3G53090
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ubiquitin-protein ligase 7
    Summary
    encodes a ubiquitin-protein ligase containing a HECT domain. There are six other HECT-domain UPLs in Arabidopsis.
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    Genomic context

    See UPL7 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    15
    Sequence:
    Chromosome: 3; NC_003074.8 (19679177..19685360)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene D-galactoside/L-rhamnose binding SUEL lectin protein Neighboring gene D-galactoside/L-rhamnose binding SUEL lectin protein Neighboring gene GDSL-like Lipase/Acylhydrolase superfamily protein Neighboring gene P-loop containing nucleoside triphosphate hydrolases superfamily protein Neighboring gene Modifier of rudimentary (Mod(r)) protein Neighboring gene Cytochrome P450 superfamily protein Neighboring gene O-methyltransferase family protein

    General gene information

    NM_001035773.2
    NM_115169.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables ubiquitin-protein transferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in protein polyubiquitination IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within protein ubiquitination ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
     
    part_of ubiquitin ligase complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 

    General protein information

    Preferred Names
    ubiquitin-protein ligase 7
    NP_001030850.1
    • ubiquitin-protein ligase 7 (UPL7); CONTAINS InterPro DOMAIN/s: HECT (InterPro:IPR000569), IQ calmodulin-binding region (InterPro:IPR000048); BEST Arabidopsis thaliana protein match is: ubiquitin protein ligase 6 (TAIR:AT3G17205.3); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_190877.1
    • ubiquitin-protein ligase 7 (UPL7); CONTAINS InterPro DOMAIN/s: HECT (InterPro:IPR000569), IQ calmodulin-binding region (InterPro:IPR000048); BEST Arabidopsis thaliana protein match is: ubiquitin protein ligase 6 (TAIR:AT3G17205.3); Has 4481 Blast hits to 4316 proteins in 248 species: Archae - 0; Bacteria - 0; Metazoa - 2549; Fungi - 797; Plants - 365; Viruses - 0; Other Eukaryotes - 770 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      19679177..19685360
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_115169.3NP_190877.1  ubiquitin-protein ligase 7 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_190877.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0WUM3, Q9SCQ2
      UniProtKB/TrEMBL
      A0A7G2EWA1
      Conserved Domains (2) summary
      smart00119
      Location:7991139
      HECTc; Domain Homologous to E6-AP Carboxyl Terminus with
      cd00078
      Location:7741140
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
    2. NM_001035773.2NP_001030850.1  ubiquitin-protein ligase 7 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001030850.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0WUM3, Q9SCQ2
      UniProtKB/TrEMBL
      A0A7G2EWA1
      Conserved Domains (2) summary
      smart00119
      Location:7991139
      HECTc; Domain Homologous to E6-AP Carboxyl Terminus with
      cd00078
      Location:7741140
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...