ATZW10 centromere/kinetochore protein, putative (ZW10) [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: ATZW10
Official Full Name: centromere/kinetochore protein, putative (ZW10)
Primary source: TAIR:AT2G32900
Locus tag: AT2G32900
See related: Araport:AT2G32900
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: T21L14.16; T21L14_16
Summary: homologous to Drosophila ZW10, a centromere/kinetochore protein involved in chromosome segregation
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Chromosome 2 - NC_003071.7 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

MAG2 and the three MIP proteins (MIP1, MIP2, MIP3) form a unique complex on the ER that is responsible for efficient transport of seed storage proteins.
Title: MAG2 and three MAG2-INTERACTING PROTEINs form an ER-localized complex to facilitate storage protein transport in Arabidopsis thaliana.
MAG2 functions as a complex with ZW10, and is potentially involved in Golgi-to-ER retrograde trafficking.
Title: MAIGO2 is involved in abscisic acid-mediated response to abiotic stresses and Golgi-to-ER retrograde transport.

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

NM_128850.3

Function	Evidence Code	Pubs
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within chromosome segregation	ISS Inferred from Sequence or Structural Similarity more info	PubMed
involved_in mitotic cell cycle	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within protein exit from endoplasmic reticulum	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within protein transport	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
colocalizes_with endoplasmic reticulum	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info
located_in nucleus	ISM Inferred from Sequence Model more info

NP_565757.2

ATZW10; INVOLVED IN: chromosome segregation; LOCATED IN: chromosome, centromeric region, nucleus; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Centromere/kinetochore protein Zw10 (InterPro:IPR009361); Has 272 Blast hits to 258 proteins in 128 species: Archae - 0; Bacteria - 2; Metazoa - 125; Fungi - 86; Plants - 38; Viruses - 0; Other Eukaryotes - 21 (source: NCBI BLink).