U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    WDR55 transducin family protein / WD-40 repeat family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 817987, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    WDR55
    Official Full Name
    transducin family protein / WD-40 repeat family protein
    Primary source
    TAIR:AT2G34260
    Locus tag
    AT2G34260
    See related
    Araport:AT2G34260
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F13P17.10; F13P17_10; human WDR55 (WD40 repeat) homolog
    Summary
    Encodes a WDxR motif-containing protein that is required for gametogenesis, seed and endosperm development.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See WDR55 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    14
    Sequence:
    Chromosome: 2; NC_003071.7 (14465516..14468547)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene ubiquitin carboxyl-terminal hydrolase-like protein, putative (Protein with domains of unknown function DUF627 and DUF632) Neighboring gene SecY protein transport family protein Neighboring gene uncharacterized protein Neighboring gene F-box and associated interaction domains-containing protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. The Arabidopsis DDB1 interacting protein WDR55 is required for vegetative development. Bjerkan KN, et al. Plant Signal Behav, 2013 Sep. PMID 23803743, Free PMC Article
    2. Arabidopsis WD repeat domain55 Interacts with DNA damaged binding protein1 and is required for apical patterning in the embryo. Bjerkan KN, et al. Plant Cell, 2012 Mar. PMID 22447688, Free PMC Article
    3. Arabidopsis DDB1-CUL4 ASSOCIATED FACTOR1 forms a nuclear E3 ubiquitin ligase with DDB1 and CUL4 that is involved in multiple plant developmental processes. Zhang Y, et al. Plant Cell, 2008 Jun. PMID 18552200, Free PMC Article
    4. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. a DDB1(WDR55) complex could regulate embryo and endosperm development.[WDR55]
      Title: The Arabidopsis DDB1 interacting protein WDR55 is required for vegetative development.
    2. WDR55-DDB1 complex is involved in the establishment of bilateral symmetry in the Arabidopsis embryo.
      Title: Arabidopsis WD repeat domain55 Interacts with DNA damaged binding protein1 and is required for apical patterning in the embryo.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help
    NM_128977.4
    NM_201867.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within determination of bilateral symmetry IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in developmental vegetative growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within embryo development ending in seed dormancy IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within embryo sac development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within endosperm development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within polar nucleus fusion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Cul4-RING E3 ubiquitin ligase complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    transducin family protein / WD-40 repeat family protein
    NP_565782.1
    • transducin family protein / WD-40 repeat family protein; FUNCTIONS IN: nucleotide binding; LOCATED IN: CUL4 RING ubiquitin ligase complex, heterotrimeric G-protein complex; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: WD40 repeat 2 (InterPro:IPR019782), WD40 repeat, conserved site (InterPro:IPR019775), WD40 repeat (InterPro:IPR001680), WD repeat protein 55 (InterPro:IPR017422), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: Transducin/WD40 repeat-like superfamily protein (TAIR:AT2G43770.1); Has 21772 Blast hits to 13043 proteins in 620 species: Archae - 50; Bacteria - 4645; Metazoa - 7300; Fungi - 4653; Plants - 2070; Viruses - 0; Other Eukaryotes - 3054 (source: NCBI BLink).
    NP_973596.1
    • transducin family protein / WD-40 repeat family protein; FUNCTIONS IN: nucleotide binding; LOCATED IN: CUL4 RING ubiquitin ligase complex, heterotrimeric G-protein complex; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: WD40 repeat 2 (InterPro:IPR019782), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40 repeat, conserved site (InterPro:IPR019775), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), WD40 repeat (InterPro:IPR001680), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: Transducin/WD40 repeat-like superfamily protein (TAIR:AT3G49660.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      14465516..14468547
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_128977.4 → NP_565782.1  transducin family protein / WD-40 repeat family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_565782.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4IGY3, O80775
      UniProtKB/TrEMBL
      A0A178VXX8, A0A5S9X3X8, A0A654EYQ8
      Conserved Domains (2) summary
      sd00039
      Location:12 → 49
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:12 → 290
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    2. NM_201867.2 → NP_973596.1  transducin family protein / WD-40 repeat family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_973596.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VXX8, A0A5S9X3X8
      Conserved Domains (3) summary
      COG2319
      Location:9 → 245
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:41 → 75
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:1 → 233
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O80775.2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.