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    ATP-PRT2 ATP phosphoribosyl transferase 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 837509, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ATP-PRT2
    Official Full Name
    ATP phosphoribosyl transferase 2
    Primary source
    TAIR:AT1G09795
    Locus tag
    AT1G09795
    See related
    Araport:AT1G09795
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATATP-PRT2; ATP phosphoribosyl transferase 2; ATP PHOSPHORIBOSYL TRANSFERASE 2; HISN1B
    Summary
    ATP phosphoribosyl transferase, catalyses first step of histidine biosynthesis
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    Genomic context

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    See ATP-PRT2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    11
    Sequence:
    Chromosome: 1; NC_003070.9 (3173534..3176910)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene COBRA-like protein 6 precursor Neighboring gene Cox19 family protein (CHCH motif) Neighboring gene ncRNA Neighboring gene Pseudouridine synthase family protein Neighboring gene ncRNA Neighboring gene evolutionarily conserved C-terminal region 11

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular cloning and characterization of ATP-phosphoribosyl transferase from Arabidopsis, a key enzyme in the histidine biosynthetic pathway. Ohta D, et al. Plant Physiol, 2000 Mar. PMID 10712555, Free PMC Article
    2. AT_CHLORO, a comprehensive chloroplast proteome database with subplastidial localization and curated information on envelope proteins. Ferro M, et al. Mol Cell Proteomics, 2010 Jun. PMID 20061580, Free PMC Article
    3. Sorting signals, N-terminal modifications and abundance of the chloroplast proteome. Zybailov B, et al. PLoS One, 2008 Apr 23. PMID 18431481, Free PMC Article
    4. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    NM_100852.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ATP phosphoribosyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables magnesium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within L-histidine biosynthetic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in L-histidine biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in chloroplast stroma HDA PubMed 

    General protein information

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    Preferred Names
    ATP phosphoribosyl transferase 2
    NP_563853.1
    • ATP phosphoribosyl transferase 2 (ATP-PRT2); FUNCTIONS IN: ATP phosphoribosyltransferase activity; INVOLVED IN: histidine biosynthetic process; LOCATED IN: chloroplast; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Histidine biosynthesis HisG: ATP phosphoribosyltransferase (InterPro:IPR001348), ATP phosphoribosyltransferase, conserved site (InterPro:IPR018198), ATP phosphoribosyltransferase, catalytic domain (InterPro:IPR013820), Histidine biosynthesis HisG, C-terminal (InterPro:IPR013115), Nitrogen regulatory PII-like, alpha/beta (InterPro:IPR011322); BEST Arabidopsis thaliana protein match is: ATP phosphoribosyl transferase 1 (TAIR:AT1G58080.1); Has 6354 Blast hits to 6354 proteins in 2167 species: Archae - 206; Bacteria - 4075; Metazoa - 2; Fungi - 141; Plants - 71; Viruses - 0; Other Eukaryotes - 1859 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      3173534..3176910
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_100852.2 → NP_563853.1  ATP phosphoribosyl transferase 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_563853.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8GSJ1, Q8L9K8, Q9SLW4
      UniProtKB/TrEMBL
      A0A5S9TIS9
      Conserved Domains (3) summary
      PLN02245
      Location:32 → 413
      PLN02245; ATP phosphoribosyl transferase
      cd13593
      Location:80 → 307
      PBP2_HisGL3; The catalytic domain of hexameric long form HisGL3; contains the type 2 periplasmic binding protein fold
      pfam08029
      Location:310 → 395
      HisG_C; HisG, C-terminal domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8GSJ1.1

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