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    SDF2 stromal cell-derived factor 2-like protein precursor [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 817049, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SDF2
    Official Full Name
    stromal cell-derived factor 2-like protein precursor
    Primary source
    TAIR:AT2G25110
    Locus tag
    AT2G25110
    See related
    Araport:AT2G25110
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    Arabidopsis thaliana STROMAL CELL-DERIVED FACTOR 2-like protein precursor; AtSDF2; ATSDF2-LIKE; ATSDL; F13D4.70; F13D4_70; stromal cell-derived factor 2-like protein precursor
    Summary
    Encodes an endoplasmic reticulum protein SDF2 (stromal-derived factor-2). Forms a complex SDF2-ERdj3B-BiP that is required for the proper accumulation of the surface-exposed leucine-rich repeat receptor kinases EFR. EFR is involved in PAMP (pathogen associated molecular patterns) triggered immunity.
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    Genomic context

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    See SDF2 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    6
    Sequence:
    Chromosome: 2; NC_003071.7 (10684118..10686347)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Polynucleotidyl transferase, ribonuclease H-like superfamily protein Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis stromal-derived Factor2 (SDF2) is a crucial target of the unfolded protein response in the endoplasmic reticulum. Schott A, et al. J Biol Chem, 2010 Jun 4. PMID 20378538, Free PMC Article
    2. Cloning, recombinant production, crystallization and preliminary X-ray diffraction analysis of SDF2-like protein from Arabidopsis thaliana. Radzimanowski J, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun, 2010 Jan 1. PMID 20057059, Free PMC Article
    3. Control of the pattern-recognition receptor EFR by an ER protein complex in plant immunity. Nekrasov V, et al. EMBO J, 2009 Nov 4. PMID 19763086, Free PMC Article
    4. Mapping the Arabidopsis organelle proteome. Dunkley TP, et al. Proc Natl Acad Sci U S A, 2006 Apr 25. PMID 16618929, Free PMC Article
    5. Advanced proteomic analyses yield a deep catalog of ubiquitylation targets in Arabidopsis. Kim DY, et al. Plant Cell, 2013 May. PMID 23667124, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Arabidopsis stromal-derived Factor2 (SDF2) is a crucial target of the unfolded protein response in the endoplasmic reticulum
      Title: Arabidopsis stromal-derived Factor2 (SDF2) is a crucial target of the unfolded protein response in the endoplasmic reticulum.
    2. The needle-shaped crystals did not diffract X-rays, while the other form diffracted to 1.95 A resolution using a synchrotron-radiation source and belonged to the hexagonal space group P6(1), with unit-cell parameters a = b = 96.1, c = 69.3 A.
      Title: Cloning, recombinant production, crystallization and preliminary X-ray diffraction analysis of SDF2-like protein from Arabidopsis thaliana.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_128068.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within defense response to bacterium IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within defense response to fungus IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within pattern recognition receptor signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in endoplasmic reticulum HDA PubMed 
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in vacuole HDA PubMed 

    General protein information

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    Preferred Names
    stromal cell-derived factor 2-like protein precursor
    NP_565585.1
    • stromal cell-derived factor 2-like protein precursor (SDF2); FUNCTIONS IN: molecular_function unknown; INVOLVED IN: defense response to bacterium, defense response to fungus, PAMP-induced immunity; LOCATED IN: endoplasmic reticulum, membrane; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: MIR (InterPro:IPR003608), MIR motif (InterPro:IPR016093); Has 1035 Blast hits to 992 proteins in 196 species: Archae - 0; Bacteria - 0; Metazoa - 386; Fungi - 512; Plants - 64; Viruses - 0; Other Eukaryotes - 73 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      10684118..10686347
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_128068.3 → NP_565585.1  stromal cell-derived factor 2-like protein precursor [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_565585.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O81720, Q93ZE8, Q9SEZ5
      UniProtKB/TrEMBL
      A0A178VQ56, A0A654EX31
      Conserved Domains (1) summary
      COG1928
      Location:39 → 218
      PMT1; Dolichyl-phosphate-mannose--protein O-mannosyl transferase [Posttranslational modification, protein turnover, chaperones]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q93ZE8.1

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