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    ELF5A-3 eukaryotic elongation factor 5A-3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 843273, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ELF5A-3
    Official Full Name
    eukaryotic elongation factor 5A-3
    Primary source
    TAIR:AT1G69410
    Locus tag
    AT1G69410
    See related
    Araport:AT1G69410
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATELF5A-3; eukaryotic elongation factor 5A-3; EUKARYOTIC ELONGATION FACTOR 5A-3; F10D13.8; F10D13_8
    Summary
    Encodes eIF5A-2, a putative eukaryotic translation initiation factor. There are three eIF5A coding genes in Arabidopsis: eIF5A-1/At1g13950, eIF5A-2/At1g26630 and eIF5A-3/At1g69410.
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    Genomic context

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    See ELF5A-3 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    4
    Sequence:
    Chromosome: 1; NC_003070.9 (26089030..26090734)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene chorismate mutase 3 Neighboring gene sporulation protein (DUF155) Neighboring gene homologue of bacterial MinE 1 Neighboring gene Transducin/WD40 repeat-like superfamily protein Neighboring gene DHHC-type zinc finger family protein Neighboring gene Son of sevenless protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis eIF5A3 influences growth and the response to osmotic and nutrient stress. Ma F, et al. Plant Cell Environ, 2010 Oct. PMID 20492553
    2. MAPK target networks in Arabidopsis thaliana revealed using functional protein microarrays. Popescu SC, et al. Genes Dev, 2009 Jan 1. PMID 19095804, Free PMC Article
    3. A proteomic strategy for global analysis of plant protein complexes. Aryal UK, et al. Plant Cell, 2014 Oct. PMID 25293756, Free PMC Article
    4. Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling. McBride Z, et al. Mol Cell Proteomics, 2017 Nov. PMID 28887381, Free PMC Article
    5. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_105608.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ribosome binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables translation elongation factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of translational elongation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in positive regulation of translational termination IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytosol HDA PubMed 
    located_in mitochondrion HDA PubMed 

    General protein information

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    Preferred Names
    eukaryotic elongation factor 5A-3
    NP_177100.1
    • eukaryotic elongation factor 5A-3 (ELF5A-3); FUNCTIONS IN: ribosome binding, RNA binding, translation elongation factor activity, translation initiation factor activity; INVOLVED IN: translational initiation, translational frameshifting, positive regulation of translational termination, peptidyl-lysine modification to hypusine, positive regulation of translational elongation; LOCATED IN: cellular_component unknown; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Nucleic acid-binding, OB-fold (InterPro:IPR012340), Translation elongation factor, IF5A, hypusine site (InterPro:IPR019769), Translation protein SH3-like, subgroup (InterPro:IPR014722), Translation elongation factor, IF5A (InterPro:IPR001884), Translation elongation factor, IF5A C-terminal (InterPro:IPR020189), Translation protein SH3-like (InterPro:IPR008991), Nucleic acid-binding, OB-fold-like (InterPro:IPR016027), KOW (InterPro:IPR005824); BEST Arabidopsis thaliana protein match is: eukaryotic elongation factor 5A-1 (TAIR:AT1G13950.1); Has 1331 Blast hits to 1330 proteins in 408 species: Archae - 255; Bacteria - 0; Metazoa - 363; Fungi - 252; Plants - 260; Viruses - 0; Other Eukaryotes - 201 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      26089030..26090734
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_105608.4 → NP_177100.1  eukaryotic elongation factor 5A-3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_177100.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q94JU4, Q9C505
      UniProtKB/TrEMBL
      A0A178WLT0, A0A5S9WT51
      Conserved Domains (1) summary
      PLN03107
      Location:1 → 158
      PLN03107; eukaryotic translation initiation factor 5A; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9C505.1

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