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    OPCL1 OPC-8:0 CoA ligase1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 838639, updated on 18-Sep-2024

    Summary

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    Official Symbol
    OPCL1
    Official Full Name
    OPC-8:0 CoA ligase1
    Primary source
    TAIR:AT1G20510
    Locus tag
    AT1G20510
    See related
    Araport:AT1G20510
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F5M15.17; F5M15_17; OPC-8:0 CoA ligase1
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    Genomic context

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    See OPCL1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    3
    Sequence:
    Chromosome: 1; NC_003070.9 (7103362..7106121, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene AMP-dependent synthetase and ligase family protein Neighboring gene AMP-dependent synthetase and ligase family protein Neighboring gene ncRNA Neighboring gene DUF241 domain protein, putative (DUF241) Neighboring gene girdin (DUF630 and DUF632)

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of a peroxisomal acyl-activating enzyme involved in the biosynthesis of jasmonic acid in Arabidopsis. Koo AJ, et al. J Biol Chem, 2006 Nov 3. PMID 16963437
    2. Jasmonates meet fatty acids: functional analysis of a new acyl-coenzyme A synthetase family from Arabidopsis thaliana. Kienow L, et al. J Exp Bot, 2008. PMID 18267944
    3. A downstream mediator in the growth repression limb of the jasmonate pathway. Yan Y, et al. Plant Cell, 2007 Aug. PMID 17675405, Free PMC Article
    4. Proteome analysis of Arabidopsis leaf peroxisomes reveals novel targeting peptides, metabolic pathways, and defense mechanisms. Reumann S, et al. Plant Cell, 2007 Oct. PMID 17951448, Free PMC Article
    5. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. catalyses an essential step in jasmonic acid biosynthesis by initiating the beta-oxidative chain shortening of the carboxylic acid side chain of its precursors
      Title: Jasmonates meet fatty acids: functional analysis of a new acyl-coenzyme A synthetase family from Arabidopsis thaliana.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    Homology

    NM_101901.4
    NM_202143.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables 4-coumarate-CoA ligase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables CoA-ligase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in jasmonic acid biosynthetic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within jasmonic acid biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in response to bacterium IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in response to jasmonic acid IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within response to wounding IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to wounding IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in peroxisome HDA PubMed 
    located_in peroxisome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    OPC-8:0 CoA ligase1
    NP_564115.1
    • OPC-8:0 CoA ligase1 (OPCL1); FUNCTIONS IN: 4-coumarate-CoA ligase activity; INVOLVED IN: phenylpropanoid metabolic process, jasmonic acid biosynthetic process, response to wounding; LOCATED IN: peroxisome; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: AMP-binding, conserved site (InterPro:IPR020845), AMP-dependent synthetase/ligase (InterPro:IPR000873); BEST Arabidopsis thaliana protein match is: AMP-dependent synthetase and ligase family protein (TAIR:AT1G20500.1); Has 85702 Blast hits to 78184 proteins in 3819 species: Archae - 1213; Bacteria - 55131; Metazoa - 3605; Fungi - 4761; Plants - 2762; Viruses - 1; Other Eukaryotes - 18229 (source: NCBI BLink).
    NP_973872.1
    • OPC-8:0 CoA ligase1 (OPCL1); FUNCTIONS IN: 4-coumarate-CoA ligase activity; INVOLVED IN: phenylpropanoid metabolic process, jasmonic acid biosynthetic process, response to wounding; LOCATED IN: peroxisome; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: AMP-binding, conserved site (InterPro:IPR020845), AMP-dependent synthetase/ligase (InterPro:IPR000873); BEST Arabidopsis thaliana protein match is: AMP-dependent synthetase and ligase family protein (TAIR:AT1G20500.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      7103362..7106121 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001332447.1 → NP_001322647.1  OPC-8:0 CoA ligase1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178W4B4, A0A1P8AUM2

    2. NM_101901.4 → NP_564115.1  OPC-8:0 CoA ligase1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_564115.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q84P21, Q9C5H2, Q9LMV8
      UniProtKB/TrEMBL
      A0A5S9VC39, A0A654EGK6, A0A7G2DRZ2
      Conserved Domains (1) summary
      cd05904
      Location:26 → 536
      4CL; 4-Coumarate-CoA Ligase (4CL)

    3. NM_202143.1 → NP_973872.1  OPC-8:0 CoA ligase1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_973872.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178W4B4, F4HST9
      Conserved Domains (2) summary
      cd05904
      Location:26 → 473
      4CL; 4-Coumarate-CoA Ligase (4CL)
      pfam00501
      Location:39 → 447
      AMP-binding; AMP-binding enzyme
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q84P21.2

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