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    MPPBETA Insulinase (Peptidase family M16) protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 821084, updated on 18-Sep-2024

    Summary

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    Official Symbol
    MPPBETA
    Official Full Name
    Insulinase (Peptidase family M16) protein
    Primary source
    TAIR:AT3G02090
    Locus tag
    AT3G02090
    See related
    Araport:AT3G02090
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F1C9.12; F1C9_12
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    Genomic context

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    See MPPBETA in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    9
    Sequence:
    Chromosome: 3; NC_003074.8 (365537..368911)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene Cysteine proteinases superfamily protein Neighboring gene Ribosomal protein S19e family protein Neighboring gene UDP-Glycosyltransferase superfamily protein Neighboring gene serine carboxypeptidase-like 25 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis PPR40 connects abiotic stress responses to mitochondrial electron transport. Zsigmond L, et al. Plant Physiol, 2008 Apr. PMID 18305213, Free PMC Article
    2. The Arabidopsis class II sirtuin is a lysine deacetylase and interacts with mitochondrial energy metabolism. König AC, et al. Plant Physiol, 2014 Mar. PMID 24424322, Free PMC Article
    3. A transcriptomic and proteomic characterization of the Arabidopsis mitochondrial protein import apparatus and its response to mitochondrial dysfunction. Lister R, et al. Plant Physiol, 2004 Feb. PMID 14730085, Free PMC Article
    4. Resolving and identifying protein components of plant mitochondrial respiratory complexes using three dimensions of gel electrophoresis. Meyer EH, et al. J Proteome Res, 2008 Feb. PMID 18189341
    5. Analysis of the Arabidopsis mitochondrial proteome. Millar AH, et al. Plant Physiol, 2001 Dec. PMID 11743115, Free PMC Article

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_111075.3
    NM_180169.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables metalloendopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables zinc ion binding HDA PubMed 
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in cytosol HDA PubMed 
    located_in mitochondrial inner membrane HDA PubMed 
    located_in mitochondrial intermembrane space HDA PubMed 
    located_in mitochondrial matrix HDA PubMed 
    located_in mitochondrial outer membrane HDA PubMed 
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleolus HDA PubMed 
    located_in plant-type cell wall HDA PubMed 
    located_in plant-type vacuole HDA PubMed 
    part_of respiratory chain complex III HDA PubMed 

    General protein information

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    Preferred Names
    Insulinase (Peptidase family M16) protein
    NP_186858.1
    • MPPBETA; FUNCTIONS IN: metalloendopeptidase activity, zinc ion binding; INVOLVED IN: proteolysis; LOCATED IN: in 11 components; EXPRESSED IN: 27 plant structures; EXPRESSED DURING: 17 growth stages; CONTAINS InterPro DOMAIN/s: Peptidase M16, zinc-binding site (InterPro:IPR001431), Peptidase M16, C-terminal (InterPro:IPR007863), Peptidase M16, N-terminal (InterPro:IPR011765), Metalloenzyme, LuxS/M16 peptidase-like, metal-binding (InterPro:IPR011249), Peptidase M16, core (InterPro:IPR011237); BEST Arabidopsis thaliana protein match is: Insulinase (Peptidase family M16) protein (TAIR:AT1G51980.1); Has 13314 Blast hits to 12840 proteins in 2395 species: Archae - 22; Bacteria - 8770; Metazoa - 1075; Fungi - 780; Plants - 366; Viruses - 3; Other Eukaryotes - 2298 (source: NCBI BLink).
    NP_850500.1
    • MPPBETA; FUNCTIONS IN: metalloendopeptidase activity, zinc ion binding; INVOLVED IN: proteolysis; LOCATED IN: in 11 components; EXPRESSED IN: 27 plant structures; EXPRESSED DURING: 17 growth stages; CONTAINS InterPro DOMAIN/s: Peptidase M16, zinc-binding site (InterPro:IPR001431), Peptidase M16, C-terminal (InterPro:IPR007863), Peptidase M16, N-terminal (InterPro:IPR011765), Metalloenzyme, LuxS/M16 peptidase-like, metal-binding (InterPro:IPR011249), Peptidase M16, core (InterPro:IPR011237); BEST Arabidopsis thaliana protein match is: Insulinase (Peptidase family M16) protein (TAIR:AT1G51980.1); Has 13067 Blast hits to 12610 proteins in 2372 species: Archae - 22; Bacteria - 8565; Metazoa - 1070; Fungi - 780; Plants - 365; Viruses - 3; Other Eukaryotes - 2262 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      365537..368911
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_111075.3 → NP_186858.1  Insulinase (Peptidase family M16) protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_186858.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0WWT6, Q42290, Q9SGA7
      UniProtKB/TrEMBL
      A0A178V9A9, A0A5S9X8W5, C0Z325
      Conserved Domains (1) summary
      COG0612
      Location:83 → 520
      PqqL; Predicted Zn-dependent peptidase [General function prediction only]

    2. NM_180169.1 → NP_850500.1  Insulinase (Peptidase family M16) protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_850500.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      C0Z325
      Conserved Domains (3) summary
      COG0612
      Location:83 → 503
      PqqL; Predicted Zn-dependent peptidase [General function prediction only]
      pfam00675
      Location:107 → 254
      Peptidase_M16; Insulinase (Peptidase family M16)
      pfam05193
      Location:260 → 446
      Peptidase_M16_C; Peptidase M16 inactive domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q42290.2

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