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    COL2 CONSTANS-like 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 821298, updated on 18-Sep-2024

    Summary

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    Official Symbol
    COL2
    Official Full Name
    CONSTANS-like 2
    Primary source
    TAIR:AT3G02380
    Locus tag
    AT3G02380
    See related
    Araport:AT3G02380
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATCOL2; B-box domain protein 3; BBX3; CONSTANS-like 2; CONSTANS-LIKE 2; F11A12.7; F11A12_7
    Summary
    homologous to the flowering-time gene CONSTANS (CO) encoding zinc-finger proteins
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    Genomic context

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    See COL2 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    2
    Sequence:
    Chromosome: 3; NC_003074.8 (487069..489467, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene galacturonosyltransferase 9 Neighboring gene 6-phosphogluconate dehydrogenase family protein Neighboring gene tRNA-splicing endonuclease subunit Neighboring gene uncharacterized protein Neighboring gene alpha/beta-Hydrolases superfamily protein Neighboring gene SMAD/FHA domain-containing protein Neighboring gene dihydroflavonol 4-reductase/flavanone protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Analysis of the function of two circadian-regulated CONSTANS-LIKE genes. Ledger S, et al. Plant J, 2001 Apr. PMID 11359606
    2. The sequence variation responsible for the functional difference between the CONSTANS protein, and the CONSTANS-like (COL) 1 and COL2 proteins, resides mostly in the region encoded by their first exons. Kim SK, et al. Plant Sci, 2013 Feb. PMID 23265320
    3. Arabidopsis TOE proteins convey a photoperiodic signal to antagonize CONSTANS and regulate flowering time. Zhang B, et al. Genes Dev, 2015 May 1. PMID 25934507, Free PMC Article
    4. Identification of LOV KELCH PROTEIN2 (LKP2)-interacting factors that can recruit LKP2 to nuclear bodies. Fukamatsu Y, et al. Plant Cell Physiol, 2005 Aug. PMID 15937324
    5. Plastids are major regulators of light signaling in Arabidopsis. Ruckle ME, et al. Plant Physiol, 2012 May. PMID 22383539, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The lack of flowering promotion activity by COL1 and COL2 is mainly attributed to the differences between CO and the COL1 and COL2 proteins in the amino acid sequence encoded by their first exons.
      Title: The sequence variation responsible for the functional difference between the CONSTANS protein, and the CONSTANS-like (COL) 1 and COL2 proteins, resides mostly in the region encoded by their first exons.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_111105.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within chloroplast organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of flower development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    CONSTANS-like 2
    NP_186887.1
    • CONSTANS-like 2 (COL2); FUNCTIONS IN: sequence-specific DNA binding transcription factor activity, zinc ion binding; INVOLVED IN: regulation of flower development; LOCATED IN: intracellular; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: CCT domain (InterPro:IPR010402), Zinc finger, B-box (InterPro:IPR000315); BEST Arabidopsis thaliana protein match is: B-box type zinc finger protein with CCT domain (TAIR:AT5G15840.1); Has 3185 Blast hits to 2478 proteins in 141 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 2995; Viruses - 0; Other Eukaryotes - 190 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      487069..489467 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_111105.3 → NP_186887.1  CONSTANS-like 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_186887.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q96502
      UniProtKB/TrEMBL
      A0A178VE79, A0A5S9X8I1
      Conserved Domains (2) summary
      cd19821
      Location:15 → 58
      Bbox1_BBX-like; B-box-type 1 zinc finger found in B-box (BBX) family of plant transcription factors and similar proteins
      pfam06203
      Location:278 → 320
      CCT; CCT motif
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q96502.1

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