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    ATHXK4 Hexokinase [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 821543, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ATHXK4
    Official Full Name
    Hexokinase
    Primary source
    TAIR:AT3G20040
    Locus tag
    AT3G20040
    See related
    Araport:AT3G20040
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    HEXOKINASE-LIKE 2; HKL2
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    Genomic context

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    See ATHXK4 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    9
    Sequence:
    Chromosome: 3; NC_003074.8 (6994770..6998185)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene F-box and associated interaction domains-containing protein Neighboring gene T-complex protein 1 alpha subunit Neighboring gene ubiquitin-conjugating enzyme19 Neighboring gene titan9

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Expression and evolutionary features of the hexokinase gene family in Arabidopsis. Karve A, et al. Planta, 2008 Aug. PMID 18481082, Free PMC Article
    2. Multiple lines of evidence localize signaling, morphology, and lipid biosynthesis machinery to the mitochondrial outer membrane of Arabidopsis. Duncan O, et al. Plant Physiol, 2011 Nov. PMID 21896887, Free PMC Article
    3. Identification and characterization of nuclear pore complex components in Arabidopsis thaliana. Tamura K, et al. Plant Cell, 2010 Dec. PMID 21189294, Free PMC Article
    4. Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins. Heazlewood JL, et al. Plant Cell, 2004 Jan. PMID 14671022, Free PMC Article
    5. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    NM_112895.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables D-glucose binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    NOT enables fructokinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    NOT enables glucokinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in glycolytic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in hexose metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in intracellular glucose homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrial outer membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Hexokinase
    NP_188639.2
    • ATHXK4; FUNCTIONS IN: hexokinase activity, ATP binding; INVOLVED IN: glucose catabolic process to butanediol, glucose catabolic process to lactate and acetate, glycolysis, carbohydrate metabolic process, glucose catabolic process to D-lactate and ethanol; LOCATED IN: mitochondrion; EXPRESSED IN: 17 plant structures; EXPRESSED DURING: 8 growth stages; CONTAINS InterPro DOMAIN/s: Hexokinase, N-terminal (InterPro:IPR022672), Hexokinase, C-terminal (InterPro:IPR022673), Hexokinase (InterPro:IPR001312); BEST Arabidopsis thaliana protein match is: hexokinase-like 1 (TAIR:AT1G50460.1); Has 2384 Blast hits to 2114 proteins in 325 species: Archae - 0; Bacteria - 92; Metazoa - 1269; Fungi - 602; Plants - 288; Viruses - 0; Other Eukaryotes - 133 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      6994770..6998185
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_112895.3 → NP_188639.2  Hexokinase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_188639.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q56XE8, Q9LJZ7
      UniProtKB/TrEMBL
      A0A178VNP2, A0A5S9XDW5, A0A7G2EM31
      Conserved Domains (1) summary
      PLN02362
      Location:1 → 502
      PLN02362; hexokinase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q56XE8.2

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