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    SAB HYPERSENSITIVE TO PI STARVATION 4 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 842193, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SAB
    Official Full Name
    HYPERSENSITIVE TO PI STARVATION 4
    Primary source
    TAIR:AT1G58250
    Locus tag
    AT1G58250
    See related
    Araport:AT1G58250
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F16M22.5; F16M22_5; HPS4; hypersensitive to Pi starvation 4; SABRE
    Summary
    SABRE, putative gene of unknown function, homologous to maize apt1 gene. Required for normal cell expansion in the root cortex. The sabre mutation results in abnormal cell expansion. Encodes a rare message; very low level of expression was detected in roots and shoots.
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    Genomic context

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    See SAB in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    24
    Sequence:
    Chromosome: 1; NC_003070.9 (21587060..21601740, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Plant thionin family protein Neighboring gene Plant thionin family protein Neighboring gene cytochrome p450 79c2 Neighboring gene Cytochrome P450 superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. HPS4/SABRE regulates plant responses to phosphate starvation through antagonistic interaction with ethylene signalling. Yu H, et al. J Exp Bot, 2012 Jul. PMID 22615140, Free PMC Article
    2. The SABRE gene is required for normal cell expansion in Arabidopsis. Aeschbacher RA, et al. Genes Dev, 1995 Feb 1. PMID 7867930
    3. Arabidopsis  SABRE and CLASP interact to stabilize cell division plane orientation and planar polarity. Pietra S, et al. Nat Commun, 2013. PMID 24240534, Free PMC Article
    4. SABRE is required for stabilization of root hair patterning in Arabidopsis thaliana. Pietra S, et al. Physiol Plant, 2015 Mar. PMID 25124848
    5. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Double mutant analysis reveal that wer and caprice (cpc) mutants, defective in core components of the epidermal patterning pathway, genetically interact with sab. This suggests that SAB may act on epidermal patterning upstream of WER and CPC.
      Title: SABRE is required for stabilization of root hair patterning in Arabidopsis thaliana.
    2. These findings mechanistically link SABRE to CLASP-dependent microtubule organization, shedding new light on the function of SABRE-related proteins in eukaryotes.
      Title: Arabidopsis  SABRE and CLASP interact to stabilize cell division plane orientation and planar polarity.
    3. HSP4 is a new allele of SABRE, which was previously identified as an important regulator of cell expansion in Arabidopsis. HPS4/SABRE antagonistically interacts with ethylene signalling to regulate plant responses to phosphate starvation.
      Title: HPS4/SABRE regulates plant responses to phosphate starvation through antagonistic interaction with ethylene signalling.
    Submit: New GeneRIF Correction

    General gene information

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    NM_001198333.1
    NM_104605.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in cellular response to phosphate starvation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in negative regulation of ethylene-activated signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of cell growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of unidimensional cell growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to ethylene IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    HYPERSENSITIVE TO PI STARVATION 4
    NP_001185262.1
    • SABRE (SAB); CONTAINS InterPro DOMAIN/s: Protein of unknown function FMP27, domain-6, C-terminal (InterPro:IPR019443), Protein of unknown function FMP27, domain-4 (InterPro:IPR019441); BEST Arabidopsis thaliana protein match is: Golgi-body localisation protein domain; RNA pol II promoter Fmp27 protein domain (TAIR:AT5G49680.2).
    NP_176121.3
    • SABRE (SAB); INVOLVED IN: response to ethylene stimulus, multidimensional cell growth, cell growth; LOCATED IN: plasma membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protein of unknown function FMP27, domain-6, C-terminal (InterPro:IPR019443), Protein of unknown function FMP27, domain-4 (InterPro:IPR019441); BEST Arabidopsis thaliana protein match is: Golgi-body localisation protein domain; RNA pol II promoter Fmp27 protein domain (TAIR:AT5G49680.2); Has 229 Blast hits to 173 proteins in 66 species: Archae - 0; Bacteria - 2; Metazoa - 113; Fungi - 17; Plants - 79; Viruses - 0; Other Eukaryotes - 18 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      21587060..21601740 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_104605.4 → NP_176121.3  HYPERSENSITIVE TO PI STARVATION 4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_176121.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4I9T5, Q0WN66, Q38969, Q6IMT1, Q9C6Q6, Q9C727
      Conserved Domains (2) summary
      pfam10347
      Location:1209 → 1304
      Fmp27_GFWDK; RNA pol II promoter Fmp27 protein domain
      pfam10351
      Location:1911 → 2447
      Apt1; Golgi-body localization protein domain

    2. NM_001198333.1 → NP_001185262.1  HYPERSENSITIVE TO PI STARVATION 4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001185262.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4I9T5, Q0WN66, Q38969, Q6IMT1, Q9C6Q6, Q9C727
      UniProtKB/TrEMBL
      F4I9T6
      Conserved Domains (2) summary
      pfam10347
      Location:1209 → 1304
      Fmp27_GFWDK; RNA pol II promoter Fmp27 protein domain
      pfam10351
      Location:1959 → 2495
      Apt1; Golgi-body localization protein domain
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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