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    U2B'' U2 small nuclear ribonucleoprotein B [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 817576, updated on 18-Sep-2024

    Summary

    Official Symbol
    U2B''
    Official Full Name
    U2 small nuclear ribonucleoprotein B
    Primary source
    TAIR:AT2G30260
    Locus tag
    AT2G30260
    See related
    Araport:AT2G30260
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    T9D9.7; T9D9_7; U2 small nuclear ribonucleoprotein B
    Summary
    encodes U2B'', which is a component of the U2 snRNP complex. Its precise role in pre-mRNA splicing is still unknown. It has been suggested that U2B0 may not be required for the splicing reaction itself but may have a role in U2 snRNP biogenesis. Deletion analysis of the U2B0 gene fusion has identified the N-terminal RNP-80 motif as sufficient for localization to the coiled body and the nucleus.
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    Genomic context

    See U2B'' in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    5
    Sequence:
    Chromosome: 2; NC_003071.7 (12905345..12907665, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene Cation/hydrogen exchanger family protein Neighboring gene WRKY DNA-binding protein 25 Neighboring gene LURP-one-like protein (DUF567) Neighboring gene RNA-directed DNA methylation 4

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    NM_001336249.1
    NM_128579.4

    Gene Ontology Provided by TAIR

    Component Evidence Code Pubs
    located_in Cajal body PubMed 
    part_of U2 snRNP PubMed 
    located_in cytoplasm PubMed 
    NOT located_in nucleolus PubMed 
    located_in nucleoplasm PubMed 
    located_in nucleus  

    General protein information

    Preferred Names
    U2 small nuclear ribonucleoprotein B
    NP_180585.1
    • U2 small nuclear ribonucleoprotein B (U2B''); FUNCTIONS IN: RNA binding, nucleotide binding, nucleic acid binding; INVOLVED IN: cis assembly of pre-catalytic spliceosome; LOCATED IN: nucleoplasm, Cajal body, cytoplasm; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: RNA recognition motif, RNP-1 (InterPro:IPR000504), Nucleotide-binding, alpha-beta plait (InterPro:IPR012677); BEST Arabidopsis thaliana protein match is: RNA-binding (RRM/RBD/RNP motifs) family protein (TAIR:AT1G06960.1); Has 1885 Blast hits to 1858 proteins in 260 species: Archae - 0; Bacteria - 2; Metazoa - 926; Fungi - 414; Plants - 327; Viruses - 1; Other Eukaryotes - 215 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      12905345..12907665 complement
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      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_128579.4 → NP_180585.1  U2 small nuclear ribonucleoprotein B [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_180585.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O22922, Q8LB63
      UniProtKB/TrEMBL
      A0A178VQB8, A0A654F858
      Conserved Domains (2) summary
      cd12246
      Location:12 → 88
      RRM1_U1A_like; RNA recognition motif 1 in the U1A/U2B"/SNF protein family
      cd12247
      Location:156 → 228
      RRM2_U1A_like; RNA recognition motif 2 in the U1A/U2B"/SNF protein family
    2. NM_001336249.1 → NP_001324159.1  U2 small nuclear ribonucleoprotein B [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VRW1, A0A1P8AZB8, A0A384K9Y7
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