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    EMB2369 tRNA synthetase class I (I, L, M and V) family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 825755, updated on 18-Sep-2024

    Summary

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    Official Symbol
    EMB2369
    Official Full Name
    tRNA synthetase class I (I, L, M and V) family protein
    Primary source
    TAIR:AT4G04350
    Locus tag
    AT4G04350
    See related
    Araport:AT4G04350
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    EMBRYO DEFECTIVE 2369; T19B17.7; T19B17_7
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    Genomic context

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    See EMB2369 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    20
    Sequence:
    Chromosome: 4; NC_003075.7 (2128090..2133150)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene malonyl-CoA decarboxylase family protein Neighboring gene Chaperonin-like RbcX protein Neighboring gene ERD (early-responsive to dehydration stress) family protein Neighboring gene transmembrane protein, putative (DUF1068) Neighboring gene Tetratricopeptide repeat (TPR)-like superfamily protein Neighboring gene miscRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Dual targeting is the rule for organellar aminoacyl-tRNA synthetases in Arabidopsis thaliana. Duchêne AM, et al. Proc Natl Acad Sci U S A, 2005 Nov 8. PMID 16251277, Free PMC Article
    2. Requirement of aminoacyl-tRNA synthetases for gametogenesis and embryo development in Arabidopsis. Berg M, et al. Plant J, 2005 Dec. PMID 16297076
    3. AT_CHLORO, a comprehensive chloroplast proteome database with subplastidial localization and curated information on envelope proteins. Ferro M, et al. Mol Cell Proteomics, 2010 Jun. PMID 20061580, Free PMC Article
    4. A proteomic strategy for global analysis of plant protein complexes. Aryal UK, et al. Plant Cell, 2014 Oct. PMID 25293756, Free PMC Article
    5. Sorting signals, N-terminal modifications and abundance of the chloroplast proteome. Zybailov B, et al. PLoS One, 2008 Apr 23. PMID 18431481, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_116673.7

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables aminoacyl-tRNA editing activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables leucine-tRNA ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within embryo development ending in seed dormancy IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within embryo development ending in seed dormancy NAS
    Non-traceable Author Statement
    more info
    		  
    involved_in leucyl-tRNA aminoacylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chloroplast stroma HDA PubMed 
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    tRNA synthetase class I (I, L, M and V) family protein
    NP_192344.1
    • EMBRYO DEFECTIVE 2369 (EMB2369); FUNCTIONS IN: aminoacyl-tRNA ligase activity, nucleotide binding, leucine-tRNA ligase activity, ATP binding; INVOLVED IN: tRNA aminoacylation for protein translation, embryo development ending in seed dormancy; LOCATED IN: mitochondrion, chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Aminoacyl-tRNA synthetase, class I, conserved site (InterPro:IPR001412), Rossmann-like alpha/beta/alpha sandwich fold (InterPro:IPR014729), Leucyl-tRNA synthetase, class Ia, bacterial/mitochondrial (InterPro:IPR002302), Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding (InterPro:IPR013155), Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing (InterPro:IPR009008), Aminoacyl-tRNA synthetase, class Ia (InterPro:IPR002300), Aminoacyl-tRNA synthetase, class 1a, anticodon-binding (InterPro:IPR009080); BEST Arabidopsis thaliana protein match is: tRNA synthetase class I (I, L, M and V) family protein (TAIR:AT5G49030.1); Has 40727 Blast hits to 36917 proteins in 3154 species: Archae - 1372; Bacteria - 23600; Metazoa - 846; Fungi - 790; Plants - 334; Viruses - 3; Other Eukaryotes - 13782 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      2128090..2133150
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_116673.7 → NP_192344.1  tRNA synthetase class I (I, L, M and V) family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_192344.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9XEA0
      UniProtKB/TrEMBL
      A0A5S9XQT3
      Conserved Domains (5) summary
      cd07958
      Location:769 → 880
      Anticodon_Ia_Leu_BEm; Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases
      cd00812
      Location:116 → 307
      LeuRS_core; catalytic core domain of leucyl-tRNA synthetases
      PLN02563
      Location:6 → 970
      PLN02563; aminoacyl-tRNA ligase
      pfam13603
      Location:303 → 498
      tRNA-synt_1_2; Leucyl-tRNA synthetase, Domain 2
      cl00015
      Location:730 → 766
      nt_trans; nucleotidyl transferase superfamily
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9XEA0.1

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