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    GIP1 AtGCP3 interacting protein 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 826539, updated on 18-Sep-2024

    Summary

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    Official Symbol
    GIP1
    Official Full Name
    AtGCP3 interacting protein 1
    Primary source
    TAIR:AT4G09550
    Locus tag
    AT4G09550
    See related
    Araport:AT4G09550
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS ATGCP3 INTERACTING PROTEIN 1; AtGCP3 interacting protein 1; ATGIP1; GCP3-Interacting Protein 1a; GIP1a; T15G18.30; T15G18_30
    Summary
    Encodes a gamma-tubulin complex protein that plays a role in gamma-tubulin complex localization, spindle stability and chromosomal segregation.
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    Genomic context

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    See GIP1 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    3
    Sequence:
    Chromosome: 4; NC_003075.7 (6039055..6040226)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene ECA1 gametogenesis related family protein Neighboring gene Protease-associated (PA) RING/U-box zinc finger family protein Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis MZT1 homologs GIP1 and GIP2 are essential for centromere architecture. Batzenschlager M, et al. Proc Natl Acad Sci U S A, 2015 Jul 14. PMID 26124146, Free PMC Article
    2. Identification of a novel small Arabidopsis protein interacting with gamma-tubulin complex protein 3. Janski N, et al. Cell Biol Int, 2008 May. PMID 18178112
    3. Arabidopsis GCP3-interacting protein 1/MOZART 1 is an integral component of the γ-tubulin-containing microtubule nucleating complex. Nakamura M, et al. Plant J, 2012 Jul. PMID 22404201
    4. The GCP3-interacting proteins GIP1 and GIP2 are required for γ-tubulin complex protein localization, spindle integrity, and chromosomal stability. Janski N, et al. Plant Cell, 2012 Mar. PMID 22427335, Free PMC Article
    5. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. GIP1/MOZART1 is an integral component of a subset of the Arabidopsis gamma-tubulin complexes.
      Title: Arabidopsis GCP3-interacting protein 1/MOZART 1 is an integral component of the γ-tubulin-containing microtubule nucleating complex.
    2. During mitosis GIPi and GIP2 play a role in gamma-tubulin complex localization, spindle stability and chromosomal segregation.
      Title: The GCP3-interacting proteins GIP1 and GIP2 are required for γ-tubulin complex protein localization, spindle integrity, and chromosomal stability.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001340622.1
    NM_117023.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables histone binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within CENP-A containing chromatin assembly IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within centromere complex assembly IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in gamma-tubulin complex localization IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within microtubule cytoskeleton organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within microtubule nucleation by microtubule organizing center IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within mitotic spindle organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of gamma-tubulin complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of gamma-tubulin ring complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in kinetochore IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in kinetochore microtubule IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  
    located_in mitotic spindle IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nuclear envelope IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nuclear outer membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in phragmoplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in preprophase band IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    AtGCP3 interacting protein 1
    NP_192693.1
    • AtGCP3 interacting protein 1 (GIP1); CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF3743 (InterPro:IPR022214); BEST Arabidopsis thaliana protein match is: Protein of unknown function (DUF3743) (TAIR:AT1G73790.1); Has 222 Blast hits to 222 proteins in 100 species: Archae - 0; Bacteria - 0; Metazoa - 54; Fungi - 64; Plants - 72; Viruses - 0; Other Eukaryotes - 32 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      6039055..6040226
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_117023.4 → NP_192693.1  AtGCP3 interacting protein 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_192693.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9M0N8
      UniProtKB/TrEMBL
      A0A178UXG2, A0A5S9XQQ7
      Conserved Domains (1) summary
      pfam12554
      Location:11 → 55
      MOZART1; Mitotic-spindle organizing gamma-tubulin ring associated

    2. NM_001340622.1 → NP_001328567.1  AtGCP3 interacting protein 1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9M0N8
      UniProtKB/TrEMBL
      A0A178UXG2, A0A5S9XQQ7
      Conserved Domains (1) summary
      pfam12554
      Location:11 → 55
      MOZART1; Mitotic-spindle organizing gamma-tubulin ring associated
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9M0N8.1

    Gene LinkOut

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