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    LOG8 Putative lysine decarboxylase family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 831068, updated on 18-Sep-2024

    Summary

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    Official Symbol
    LOG8
    Official Full Name
    Putative lysine decarboxylase family protein
    Primary source
    TAIR:AT5G11950
    Locus tag
    AT5G11950
    See related
    Araport:AT5G11950
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F14F18.120; F14F18_120; LONELY GUY 8
    Summary
    Encodes a protein of unknown function. It has been crystallized and shown to be structurally almost identical to the protein encoded by At2G37210.
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    Genomic context

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    See LOG8 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    9
    Sequence:
    Chromosome: 5; NC_003076.8 (3854388..3857243)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Thioredoxin superfamily protein Neighboring gene Subtilase family protein Neighboring gene magnesium transporter, putative (DUF803) Neighboring gene ABC family ABC transporter, putative (DUF3511) Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. X-ray crystal structures of the conserved hypothetical proteins from Arabidopsis thaliana gene loci At5g11950 and AT2g37210. Jeon WB, et al. Proteins, 2006 Dec 1. PMID 17048257
    2. Direct control of shoot meristem activity by a cytokinin-activating enzyme. Kurakawa T, et al. Nature, 2007 Feb 8. PMID 17287810
    3. Functional analyses of LONELY GUY cytokinin-activating enzymes reveal the importance of the direct activation pathway in Arabidopsis. Kuroha T, et al. Plant Cell, 2009 Oct. PMID 19837870, Free PMC Article
    4. Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling. McBride Z, et al. Mol Cell Proteomics, 2017 Nov. PMID 28887381, Free PMC Article
    5. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Results strongly suggest that the direct activation pathway via LOGs plays a pivotal role in regulating cytokinin activity during normal growth and development in Arabidopsis.
      Title: Functional analyses of LONELY GUY cytokinin-activating enzymes reveal the importance of the direct activation pathway in Arabidopsis.
    2. X-ray crystal structures of the conserved hypothetical proteins from Arabidopsis thaliana gene loci At5g11950
      Title: X-ray crystal structures of the conserved hypothetical proteins from Arabidopsis thaliana gene loci At5g11950 and AT2g37210.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    NM_121233.4
    NM_203039.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables cytokinin riboside 5'-monophosphate phosphoribohydrolase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cytokinin biosynthetic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane HDA PubMed 

    General protein information

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    Preferred Names
    Putative lysine decarboxylase family protein
    NP_196756.2
    • Putative lysine decarboxylase family protein; FUNCTIONS IN: protein homodimerization activity; INVOLVED IN: lysine biosynthetic process via diaminopimelate; LOCATED IN: cytosol, nucleus; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Conserved hypothetical protein CHP00730 (InterPro:IPR005269); BEST Arabidopsis thaliana protein match is: lysine decarboxylase family protein (TAIR:AT2G37210.1); Has 4835 Blast hits to 4834 proteins in 1455 species: Archae - 28; Bacteria - 3320; Metazoa - 8; Fungi - 132; Plants - 375; Viruses - 0; Other Eukaryotes - 972 (source: NCBI BLink).
    NP_974768.1
    • Putative lysine decarboxylase family protein; CONTAINS InterPro DOMAIN/s: Conserved hypothetical protein CHP00730 (InterPro:IPR005269); BEST Arabidopsis thaliana protein match is: lysine decarboxylase family protein (TAIR:AT2G37210.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      3854388..3857243
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001343223.1 → NP_001332403.1  Putative lysine decarboxylase family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0WTA9, Q570P8, Q84MC2, Q9LYH8
      UniProtKB/TrEMBL
      A0A178UJ28, A0A5S9Y3R9
      Conserved Domains (1) summary
      pfam03641
      Location:54 → 183
      Lysine_decarbox; Possible lysine decarboxylase

    2. NM_001343224.1 → NP_001332404.1  Putative lysine decarboxylase family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BGT5

    3. NM_203039.3 → NP_974768.1  Putative lysine decarboxylase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_974768.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0WTA9, Q570P8, Q84MC2, Q9LYH8
      UniProtKB/TrEMBL
      A0A178UJ28, A0A5S9Y3R9
      Conserved Domains (1) summary
      pfam03641
      Location:54 → 183
      Lysine_decarbox; Possible lysine decarboxylase

    4. NM_121233.4 → NP_196756.2  Putative lysine decarboxylase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_196756.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0WTA9, Q570P8, Q84MC2, Q9LYH8
      UniProtKB/TrEMBL
      A0A178UJ28, A0A5S9Y3R9
      Conserved Domains (1) summary
      pfam03641
      Location:54 → 183
      Lysine_decarbox; Possible lysine decarboxylase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q84MC2.1

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