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    Thiamine pyrophosphate dependent pyruvate decarboxylase family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 829444, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Thiamine pyrophosphate dependent pyruvate decarboxylase family protein
    Primary source
    TAIR:AT4G33070
    Locus tag
    AT4G33070
    See related
    Araport:AT4G33070
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtPDC1; F4I10.4; PDC1; pyruvate decarboxylase 1
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    Genomic context

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    Location:
    chromosome: 4
    Exon count:
    5
    Sequence:
    Chromosome: 4; NC_003075.7 (15952257..15954803, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene calmodulin-binding family protein Neighboring gene Cyclophilin-like peptidyl-prolyl cis-trans isomerase family protein Neighboring gene ncRNA Neighboring gene AGC (cAMP-dependent, cGMP-dependent and protein kinase C) kinase family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The pyruvate decarboxylase1 gene of Arabidopsis is required during anoxia but not other environmental stresses. Kürsteiner O, et al. Plant Physiol, 2003 Jun. PMID 12805625, Free PMC Article
    2. Reciprocal modulation of responses to nitrate starvation and hypoxia in roots and leaves of Arabidopsis thaliana. Safavi-Rizi V, et al. Plant Signal Behav, 2024 Dec 31. PMID 38165809, Free PMC Article
    3. Identification of enzymes for adenosine-to-inosine editing and discovery of cytidine-to-uridine editing in nucleus-encoded transfer RNAs of Arabidopsis. Zhou W, et al. Plant Physiol, 2014 Dec. PMID 25315605, Free PMC Article
    4. Integrative Analysis from the Epigenome to Translatome Uncovers Patterns of Dominant Nuclear Regulation during Transient Stress. Lee TA, et al. Plant Cell, 2019 Nov. PMID 31519798, Free PMC Article
    5. Advanced proteomic analyses yield a deep catalog of ubiquitylation targets in Arabidopsis. Kim DY, et al. Plant Cell, 2013 May. PMID 23667124, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_119461.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables magnesium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables pyruvate decarboxylase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables thiamine pyrophosphate binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within cellular response to hypoxia HEP PubMed 
    involved_in response to anoxia IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in response to hypoxia IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to nitrate starvation IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plasma membrane HDA PubMed 

    General protein information

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    Preferred Names
    Thiamine pyrophosphate dependent pyruvate decarboxylase family protein
    NP_195033.1
    • Thiamine pyrophosphate dependent pyruvate decarboxylase family protein; FUNCTIONS IN: in 6 functions; LOCATED IN: membrane; EXPRESSED IN: 11 plant structures; EXPRESSED DURING: 4 anthesis, C globular stage, F mature embryo stage, petal differentiation and expansion stage, E expanded cotyledon stage; CONTAINS InterPro DOMAIN/s: TPP-binding enzyme, conserved site (InterPro:IPR000399), Thiamine pyrophosphate enzyme, central domain (InterPro:IPR012000), Pyruvate decarboxylase/indolepyruvate decarboxylase (InterPro:IPR012110), Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain (InterPro:IPR012001), Thiamine pyrophosphate enzyme, C-terminal TPP-binding (InterPro:IPR011766); BEST Arabidopsis thaliana protein match is: Thiamine pyrophosphate dependent pyruvate decarboxylase family protein (TAIR:AT5G01320.1); Has 20589 Blast hits to 20526 proteins in 2548 species: Archae - 428; Bacteria - 13367; Metazoa - 177; Fungi - 761; Plants - 551; Viruses - 4; Other Eukaryotes - 5301 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      15952257..15954803 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_119461.4 → NP_195033.1  Thiamine pyrophosphate dependent pyruvate decarboxylase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_195033.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O82647, Q96535
      UniProtKB/TrEMBL
      A0A178UXD2, A0A5S9XYK2, A0A654FV05
      Conserved Domains (1) summary
      PLN02573
      Location:30 → 607
      PLN02573; pyruvate decarboxylase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O82647.1

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