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    MBR2 RING/U-box superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 829550, updated on 18-Sep-2024

    Summary

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    Official Symbol
    MBR2
    Official Full Name
    RING/U-box superfamily protein
    Primary source
    TAIR:AT4G34040
    Locus tag
    AT4G34040
    See related
    Araport:AT4G34040
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F28A23.200; F28A23_200; MED25 BINDING RING-H2 PROTEIN 2
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    Genomic context

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    See MBR2 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    7
    Sequence:
    Chromosome: 4; NC_003075.7 (16304215..16308801, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene 3-methylcrotonyl-CoA carboxylase Neighboring gene tRNA-Arg Neighboring gene S-adenosyl-L-methionine-dependent methyltransferases superfamily protein Neighboring gene demeter-like protein 3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Proteasome-mediated turnover of Arabidopsis MED25 is coupled to the activation of FLOWERING LOCUS T transcription. Iñigo S, et al. Plant Physiol, 2012 Nov. PMID 22992513, Free PMC Article
    2. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_119565.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in vegetative to reproductive phase transition of meristem IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    RING/U-box superfamily protein
    NP_195130.1
    • RING/U-box superfamily protein; FUNCTIONS IN: zinc ion binding; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Zinc finger, RING-type (InterPro:IPR001841), Zinc finger, C3HC4 RING-type (InterPro:IPR018957); BEST Arabidopsis thaliana protein match is: RING/U-box superfamily protein (TAIR:AT2G15530.3); Has 8873 Blast hits to 7809 proteins in 315 species: Archae - 0; Bacteria - 89; Metazoa - 2441; Fungi - 580; Plants - 3871; Viruses - 41; Other Eukaryotes - 1851 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      16304215..16308801 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_119565.4 → NP_195130.1  RING/U-box superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_195130.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O49500
      UniProtKB/TrEMBL
      A0A5S9XYF8, A0A654FVE9
      Conserved Domains (3) summary
      pfam10630
      Location:411 → 477
      DUF2476; Protein of unknown function (DUF2476)
      pfam12678
      Location:616 → 660
      zf-rbx1; RING-H2 zinc finger
      pfam13639
      Location:619 → 660
      zf-RING_2; Ring finger domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O49500.1

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