U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    SEN1 splicing endonuclease 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 823701, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    SEN1
    Official Full Name
    splicing endonuclease 1
    Primary source
    TAIR:AT3G45590
    Locus tag
    AT3G45590
    See related
    Araport:AT3G45590
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATSEN1; splicing endonuclease 1
    Summary
    Encodes a catalytic subunit of tRNA splicing endonuclease.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See SEN1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    2
    Sequence:
    Chromosome: 3; NC_003074.8 (16732540..16733854)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene tRNA-intron endonuclease Neighboring gene RING/U-box protein with C6HC-type zinc finger Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene tetraspanin3 Neighboring gene Dof-type zinc finger DNA-binding family protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    NM_001084776.2
    NM_114428.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables tRNA-intron endonuclease activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in tRNA splicing, via endonucleolytic cleavage and ligation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    splicing endonuclease 1
    NP_001078245.1
    • splicing endonuclease 1 (SEN1); FUNCTIONS IN: tRNA-intron endonuclease activity, nuclease activity, nucleic acid binding; INVOLVED IN: tRNA splicing, via endonucleolytic cleavage and ligation; LOCATED IN: tRNA-intron endonuclease complex; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: tRNA-intron endonuclease (InterPro:IPR006676), tRNA intron endonuclease, catalytic domain-like (InterPro:IPR006677), Endonuclease TnsA, N-terminal/resolvase Hjc/tRNA endonuclease, C-terminal (InterPro:IPR011856), tRNA intron endonuclease, N-terminal (InterPro:IPR006678); BEST Arabidopsis thaliana protein match is: splicing endonuclease 2 (TAIR:AT5G60230.2); Has 489 Blast hits to 489 proteins in 224 species: Archae - 131; Bacteria - 0; Metazoa - 123; Fungi - 137; Plants - 68; Viruses - 0; Other Eukaryotes - 30 (source: NCBI BLink).
    NP_190145.1
    • splicing endonuclease 1 (SEN1); FUNCTIONS IN: tRNA-intron endonuclease activity, nucleic acid binding, nuclease activity; INVOLVED IN: tRNA splicing, via endonucleolytic cleavage and ligation; LOCATED IN: tRNA-intron endonuclease complex; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: tRNA-intron endonuclease (InterPro:IPR006676), tRNA intron endonuclease, catalytic domain-like (InterPro:IPR006677), Endonuclease TnsA, N-terminal/resolvase Hjc/tRNA endonuclease, C-terminal (InterPro:IPR011856), tRNA intron endonuclease, N-terminal (InterPro:IPR006678); BEST Arabidopsis thaliana protein match is: splicing endonuclease 2 (TAIR:AT5G60230.2); Has 489 Blast hits to 489 proteins in 224 species: Archae - 131; Bacteria - 0; Metazoa - 123; Fungi - 137; Plants - 68; Viruses - 0; Other Eukaryotes - 30 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      16732540..16733854
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_114428.4 → NP_190145.1  splicing endonuclease 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_190145.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9M1E8, Q9S7L3
      UniProtKB/TrEMBL
      A0A5S9XJR3, A0A7G2ERH0, Q2HIF6
      Conserved Domains (2) summary
      pfam02778
      Location:35 → 108
      tRNA_int_endo_N; tRNA intron endonuclease, N-terminal domain
      cd22363
      Location:117 → 224
      tRNA-intron_lyase_C; catalytic C-terminal domain of the tRNA-intron lyase

    2. NM_001084776.2 → NP_001078245.1  splicing endonuclease 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001078245.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9M1E8, Q9S7L3
      UniProtKB/TrEMBL
      A0A5S9XJR3, A0A7G2ERH0, Q2HIF6
      Conserved Domains (2) summary
      pfam02778
      Location:35 → 108
      tRNA_int_endo_N; tRNA intron endonuclease, N-terminal domain
      cd22363
      Location:117 → 224
      tRNA-intron_lyase_C; catalytic C-terminal domain of the tRNA-intron lyase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9M1E8.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools