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    UEV1D-4 ubiquitin E2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 824422, updated on 18-Sep-2024

    Summary

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    Official Symbol
    UEV1D-4
    Official Full Name
    ubiquitin E2
    Primary source
    TAIR:AT3G52560
    Locus tag
    AT3G52560
    See related
    Araport:AT3G52560
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F3C22.2; MMS2 ZWEI HOMOLOGUE 4; MMZ4; UBIQUITIN E2 VARIANT 1D; ubiquitin E2 variant 1D-4; UEV1D
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    Genomic context

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    See UEV1D-4 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    4
    Sequence:
    Chromosome: 3; NC_003074.8 (19494369..19496147, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ovate family protein 18 Neighboring gene transcription repressor OFP15-like protein Neighboring gene uncharacterized protein Neighboring gene tRNA-Leu

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis UEV1D promotes Lysine-63-linked polyubiquitination and is involved in DNA damage response. Wen R, et al. Plant Cell, 2008 Jan. PMID 18178771, Free PMC Article
    2. Targeted interactomics reveals a complex core cell cycle machinery in Arabidopsis thaliana. Van Leene J, et al. Mol Syst Biol, 2010 Aug 10. PMID 20706207, Free PMC Article
    3. A proteomic strategy for global analysis of plant protein complexes. Aryal UK, et al. Plant Cell, 2014 Oct. PMID 25293756, Free PMC Article
    4. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article
    5. Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling. McBride Z, et al. Mol Cell Proteomics, 2017 Nov. PMID 28887381, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. UEV1D appears to express at a much higher level in germinating seeds and in pollen.
      Title: Arabidopsis UEV1D promotes Lysine-63-linked polyubiquitination and is involved in DNA damage response.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001084803.1
    NM_001203144.1
    NM_180353.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA damage response IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within positive regulation of protein polyubiquitination IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within postreplication repair IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of UBC13-MMS2 complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    located_in cytosol HDA PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    ubiquitin E2
    NP_001078272.1
    • ubiquitin E2 variant 1D-4 (UEV1D-4); CONTAINS InterPro DOMAIN/s: Ubiquitin-conjugating enzyme/RWD-like (InterPro:IPR016135), Ubiquitin-conjugating enzyme, E2 (InterPro:IPR000608); BEST Arabidopsis thaliana protein match is: MMS ZWEI homologue 3 (TAIR:AT2G36060.2); Has 1152 Blast hits to 1152 proteins in 227 species: Archae - 0; Bacteria - 0; Metazoa - 609; Fungi - 146; Plants - 247; Viruses - 0; Other Eukaryotes - 150 (source: NCBI BLink).
    NP_001190073.1
    • ubiquitin E2 variant 1D-4 (UEV1D-4); CONTAINS InterPro DOMAIN/s: Ubiquitin-conjugating enzyme/RWD-like (InterPro:IPR016135), Ubiquitin-conjugating enzyme, E2 (InterPro:IPR000608); BEST Arabidopsis thaliana protein match is: MMS ZWEI homologue 3 (TAIR:AT2G36060.2).
    NP_566968.1
    • ubiquitin E2 variant 1D-4 (UEV1D-4); CONTAINS InterPro DOMAIN/s: Ubiquitin-conjugating enzyme/RWD-like (InterPro:IPR016135), Ubiquitin-conjugating enzyme, E2 (InterPro:IPR000608); BEST Arabidopsis thaliana protein match is: MMS ZWEI homologue 3 (TAIR:AT2G36060.1); Has 2665 Blast hits to 2665 proteins in 275 species: Archae - 0; Bacteria - 0; Metazoa - 1316; Fungi - 370; Plants - 595; Viruses - 0; Other Eukaryotes - 384 (source: NCBI BLink).
    NP_850684.1
    • ubiquitin E2 variant 1D-4 (UEV1D-4); CONTAINS InterPro DOMAIN/s: Ubiquitin-conjugating enzyme/RWD-like (InterPro:IPR016135), Ubiquitin-conjugating enzyme, E2 (InterPro:IPR000608); BEST Arabidopsis thaliana protein match is: MMS ZWEI homologue 3 (TAIR:AT2G36060.2); Has 1301 Blast hits to 1301 proteins in 235 species: Archae - 0; Bacteria - 0; Metazoa - 663; Fungi - 165; Plants - 298; Viruses - 0; Other Eukaryotes - 175 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      19494369..19496147 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_115116.4 → NP_566968.1  ubiquitin E2 variant 1D-4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_566968.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A8MSC0, Q3EAL0, Q9SVD7
      UniProtKB/TrEMBL
      A0A178VID5, A0A5S9XK78, A0A7G2EFT3
      Conserved Domains (1) summary
      cl00154
      Location:13 → 143
      UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...

    2. NM_001203144.1 → NP_001190073.1  ubiquitin E2 variant 1D-4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001190073.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4J6Z1
      Conserved Domains (1) summary
      cl00154
      Location:17 → 143
      UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...

    3. NM_180353.2 → NP_850684.1  ubiquitin E2 variant 1D-4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_850684.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VKZ7, A0A7G2EFT3
      Conserved Domains (1) summary
      cl00154
      Location:13 → 144
      UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...

    4. NM_001084803.1 → NP_001078272.1  ubiquitin E2 variant 1D-4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001078272.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9SVD7
      Conserved Domains (1) summary
      cl00154
      Location:9 → 89
      UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SVD7.1

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