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    CRD1 dicarboxylate diiron protein, putative (Crd1) [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 824861, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CRD1
    Official Full Name
    dicarboxylate diiron protein, putative (Crd1)
    Primary source
    TAIR:AT3G56940
    Locus tag
    AT3G56940
    See related
    Araport:AT3G56940
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ACSF; CHL27; COPPER RESPONSE DEFECT 1; T8M16.1
    Summary
    Encodes a putative ZIP protein with varying mRNA accumulation in leaves, stems and roots. Has a consensus carboxylate-bridged di-iron binding site.
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    Genomic context

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    See CRD1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    5
    Sequence:
    Chromosome: 3; NC_003074.8 (21076505..21078443)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene DHHC-type zinc finger family protein Neighboring gene DHHC-type zinc finger family protein Neighboring gene ncRNA Neighboring gene small and basic intrinsic protein 2;1 Neighboring gene ncRNA Neighboring gene phosphatidyl inositol monophosphate 5 kinase 4 Neighboring gene basic helix-loop-helix (bHLH) DNA-binding superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Role of Arabidopsis CHL27 protein for photosynthesis, chloroplast development and gene expression profiling. Bang WY, et al. Plant Cell Physiol, 2008 Sep. PMID 18682427
    2. Arabidopsis CHL27, located in both envelope and thylakoid membranes, is required for the synthesis of protochlorophyllide. Tottey S, et al. Proc Natl Acad Sci U S A, 2003 Dec 23. PMID 14673103, Free PMC Article
    3. [Identification and tissue-specific expression of a full length cDNA encoding ZIP protein in Arabidopsis]. Zheng CC, et al. Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai), 2002 Jan. PMID 11958125
    4. PAPP5 is involved in the tetrapyrrole mediated plastid signalling during chloroplast development. Barajas-López Jde D, et al. PLoS One, 2013. PMID 23555952, Free PMC Article
    5. Potential roles of YCF54 and ferredoxin-NADPH reductase for magnesium protoporphyrin monomethylester cyclase. Herbst J, et al. Plant J, 2018 May. PMID 29443418

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001203183.1
    NM_115553.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA binding TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables mRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase activity NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chlorophyll biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within chlorophyll biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within chloroplast organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of tetrapyrrole metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in chloroplast envelope HDA PubMed 
    located_in chloroplast inner membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chloroplast thylakoid HDA PubMed 
    located_in chloroplast thylakoid membrane HDA PubMed 
    located_in chloroplast thylakoid membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    dicarboxylate diiron protein, putative (Crd1)
    NP_001190112.1
    • COPPER RESPONSE DEFECT 1 (CRD1); FUNCTIONS IN: magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase activity, DNA binding; INVOLVED IN: chlorophyll biosynthetic process, oxidation reduction, photosynthesis; LOCATED IN: chloroplast thylakoid membrane, chloroplast inner membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Magnesium-protoporphyrin IX monomethyl ester aerobic oxidative cyclase (InterPro:IPR008434), Ferritin/ribonucleotide reductase-like (InterPro:IPR009078), Rubrerythrin (InterPro:IPR003251).
    NP_191253.1
    • COPPER RESPONSE DEFECT 1 (CRD1); FUNCTIONS IN: magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase activity, DNA binding; INVOLVED IN: chlorophyll biosynthetic process, oxidation reduction, photosynthesis; LOCATED IN: chloroplast thylakoid membrane, chloroplast, chloroplast inner membrane, chloroplast envelope; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Magnesium-protoporphyrin IX monomethyl ester aerobic oxidative cyclase (InterPro:IPR008434), Ferritin/ribonucleotide reductase-like (InterPro:IPR009078), Rubrerythrin (InterPro:IPR003251); Has 877 Blast hits to 876 proteins in 230 species: Archae - 0; Bacteria - 301; Metazoa - 0; Fungi - 0; Plants - 215; Viruses - 0; Other Eukaryotes - 361 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      21076505..21078443
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_115553.4 → NP_191253.1  dicarboxylate diiron protein, putative (Crd1) [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_191253.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O04051, Q38892, Q8GUS3, Q9M1K4, Q9M591
      UniProtKB/TrEMBL
      A0A178VH55, A0A5S9XM90
      Conserved Domains (1) summary
      PLN02508
      Location:60 → 409
      PLN02508; magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase

    2. NM_001203183.1 → NP_001190112.1  dicarboxylate diiron protein, putative (Crd1) [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001190112.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4J0U9
      Conserved Domains (1) summary
      cl00264
      Location:1 → 332
      Ferritin_like; Ferritin-like superfamily of diiron-containing four-helix-bundle proteins
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9M591.2

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