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    nuclease [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 825502, updated on 18-Sep-2024

    Summary

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    Official Full Name
    nuclease
    Primary source
    TAIR:AT3G63270
    Locus tag
    AT3G63270
    See related
    Araport:AT3G63270
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
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    Genomic context

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    Location:
    chromosome: 3
    Exon count:
    3
    Sequence:
    Chromosome: 3; NC_003074.8 (23375584..23377661, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene homocysteine methyltransferase 2 Neighboring gene uncharacterized protein Neighboring gene Protein kinase superfamily protein Neighboring gene NIMA-related kinase 4 Neighboring gene 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Fast isogenic mapping-by-sequencing of ethyl methanesulfonate-induced mutant bulks. Hartwig B, et al. Plant Physiol, 2012 Oct. PMID 22837357, Free PMC Article
    2. Kicking against the PRCs - A Domesticated Transposase Antagonises Silencing Mediated by Polycomb Group Proteins and Is an Accessory Component of Polycomb Repressive Complex 2. Liang SC, et al. PLoS Genet, 2015 Dec. PMID 26642436, Free PMC Article
    3. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. ALP1 is the first example of a domesticated transposase acquiring a novel function as a PcG component. [ALP1]
      Title: Kicking against the PRCs - A Domesticated Transposase Antagonises Silencing Mediated by Polycomb Group Proteins and Is an Accessory Component of Polycomb Repressive Complex 2.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    NM_116192.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables chromatin binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in epigenetic regulation of gene expression IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of ESC/E(Z) complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of ESC/E(Z) complex IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    part_of PRC1 complex IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    nuclease
    NP_567144.1
    • CONTAINS InterPro DOMAIN/s: Putative harbinger transposase-derived nuclease (InterPro:IPR006912); BEST Arabidopsis thaliana protein match is: PIF / Ping-Pong family of plant transposases (TAIR:AT3G55350.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      23375584..23377661 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_116192.4 → NP_567144.1  nuclease [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_567144.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q94K49, Q9M1W3
      UniProtKB/TrEMBL
      A0A178V622, A0A5S9XNA7, A0A654FKB6
      Conserved Domains (2) summary
      cl21459
      Location:90 → 136
      HTH; Helix-turn-helix domains
      cl21562
      Location:183 → 348
      DDE_Tnp_4; DDE superfamily endonuclease
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q94K49.1

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