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    Hsp70-2 Heat shock protein 70 (Hsp 70) family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 831856, updated on 18-Sep-2024

    Summary

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    Official Symbol
    Hsp70-2
    Official Full Name
    Heat shock protein 70 (Hsp 70) family protein
    Primary source
    TAIR:AT5G02490
    Locus tag
    AT5G02490
    See related
    Araport:AT5G02490
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtHsp70-2; T22P11.80; T22P11_80
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    Genomic context

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    See Hsp70-2 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    2
    Sequence:
    Chromosome: 5; NC_003076.8 (550035..552827, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene HSP20-like chaperones superfamily protein Neighboring gene heat shock cognate protein 70-1 Neighboring gene Oligosaccaryltransferase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cytosolic HSC70s repress heat stress tolerance and enhance seed germination under salt stress conditions. Zhao H, et al. Plant Cell Environ, 2021 Jun. PMID 33506954
    2. AtHsp70-15-deficient Arabidopsis plants are characterized by reduced growth, a constitutive cytosolic protein response and enhanced resistance to TuMV. Jungkunz I, et al. Plant J, 2011 Jun. PMID 21418353
    3. Virus induction of heat shock protein 70 reflects a general response to protein accumulation in the plant cytosol. Aparicio F, et al. Plant Physiol, 2005 May. PMID 15805473, Free PMC Article
    4. Opposing Effects on Two Phases of Defense Responses from Concerted Actions of HEAT SHOCK COGNATE70 and BONZAI1 in Arabidopsis. Gou M, et al. Plant Physiol, 2015 Nov. PMID 26408532, Free PMC Article
    5. Interaction between SGT1 and cytosolic/nuclear HSC70 chaperones regulates Arabidopsis immune responses. Noël LD, et al. Plant Cell, 2007 Dec. PMID 18065690, Free PMC Article

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Cytosolic HSC70s repress heat stress tolerance and enhance seed germination under salt stress conditions.
      Title: Cytosolic HSC70s repress heat stress tolerance and enhance seed germination under salt stress conditions.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_120327.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ATP-dependent protein folding chaperone IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within protein folding TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within response to bacterium IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to heat IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to heat IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to virus IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus HDA PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytosol HDA PubMed 
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytosol TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plant-type cell wall HDA PubMed 
    located_in plasma membrane HDA PubMed 

    General protein information

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    Preferred Names
    Heat shock protein 70 (Hsp 70) family protein
    NP_195869.1
    • Heat shock protein 70 (Hsp 70) family protein; FUNCTIONS IN: protein binding; INVOLVED IN: protein folding, response to cadmium ion, response to heat, response to bacterium; LOCATED IN: cytosol, cell wall, plasma membrane; EXPRESSED IN: 19 plant structures; EXPRESSED DURING: 10 growth stages; CONTAINS InterPro DOMAIN/s: Heat shock protein 70, conserved site (InterPro:IPR018181), Heat shock protein Hsp70 (InterPro:IPR001023), Heat shock protein 70 (InterPro:IPR013126); BEST Arabidopsis thaliana protein match is: heat shock cognate protein 70-1 (TAIR:AT5G02500.1); Has 34231 Blast hits to 33880 proteins in 4856 species: Archae - 163; Bacteria - 16495; Metazoa - 3845; Fungi - 1761; Plants - 1263; Viruses - 309; Other Eukaryotes - 10395 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      550035..552827 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_120327.5 → NP_195869.1  Heat shock protein 70 (Hsp 70) family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_195869.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O04293, P22954, Q0WUQ6, Q56WH2, Q9LZ53
      UniProtKB/TrEMBL
      A0A178UTH3, A0A5S9Y0Q6, A0A7G2ELB8
      Conserved Domains (1) summary
      PTZ00009
      Location:5 → 653
      PTZ00009; heat shock 70 kDa protein; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P22954.2

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