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    WD40/YVTN repeat and Bromo-WDR9-I-like domain-containing protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 835003, updated on 18-Sep-2024

    Summary

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    Official Full Name
    WD40/YVTN repeat and Bromo-WDR9-I-like domain-containing protein
    Primary source
    TAIR:AT5G49430
    Locus tag
    AT5G49430
    See related
    Araport:AT5G49430
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    K7J8.10; K7J8_10
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    Genomic context

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    Location:
    chromosome: 5
    Exon count:
    25
    Sequence:
    Chromosome: 5; NC_003076.8 (20036988..20046702, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene thiamine-phosphate synthase Neighboring gene MADS-box transcription factor family protein Neighboring gene tRNA-His Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterization of Arabidopsis and rice DWD proteins and their roles as substrate receptors for CUL4-RING E3 ubiquitin ligases. Lee JH, et al. Plant Cell, 2008 Jan. PMID 18223036, Free PMC Article
    2. Arabidopsis DDB1-CUL4 ASSOCIATED FACTOR1 forms a nuclear E3 ubiquitin ligase with DDB1 and CUL4 that is involved in multiple plant developmental processes. Zhang Y, et al. Plant Cell, 2008 Jun. PMID 18552200, Free PMC Article
    3. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_001344843.1
    NM_124320.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    part_of Cul4-RING E3 ubiquitin ligase complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    WD40/YVTN repeat and Bromo-WDR9-I-like domain-containing protein
    NP_001318768.1
    • WD40/YVTN repeat-like-containing domain;Bromodomain; CONTAINS InterPro DOMAIN/s: WD40 repeat 2 (InterPro:IPR019782), WD40 repeat, conserved site (InterPro:IPR019775), WD40 repeat (InterPro:IPR001680), Bromodomain (InterPro:IPR001487), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: WD40/YVTN repeat-like-containing domain;Bromodomain (TAIR:AT2G47410.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      20036988..20046702 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001344843.1 → NP_001318768.1  WD40/YVTN repeat and Bromo-WDR9-I-like domain-containing protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UHT9, A0A654G9G5, F4K639
      Conserved Domains (4) summary
      cd05529
      Location:1548 → 1677
      Bromo_WDR9_I_like; Bromodomain; WDR9 repeat I_like subfamily. WDR9 is a human gene located in the Down Syndrome critical region-2 of chromosome 21. It encodes for a nuclear protein containing WD40 repeats and two bromodomains, which may function as a transcriptional ...
      cd00200
      Location:237 → 615
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:248 → 285
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:578 → 660
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    2. NM_124320.3 → NP_199754.2  WD40/YVTN repeat and Bromo-WDR9-I-like domain-containing protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_199754.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UHT9, A0A654G9G5, F4K639
      Conserved Domains (4) summary
      cd05529
      Location:1548 → 1677
      Bromo_WDR9_I_like; Bromodomain; WDR9 repeat I_like subfamily. WDR9 is a human gene located in the Down Syndrome critical region-2 of chromosome 21. It encodes for a nuclear protein containing WD40 repeats and two bromodomains, which may function as a transcriptional ...
      cd00200
      Location:237 → 615
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:248 → 285
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:578 → 660
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    Nucleotide Protein
    Heading Accession and Version

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