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    RAN3 RAN GTPase 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 835612, updated on 18-Sep-2024

    Summary

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    Official Symbol
    RAN3
    Official Full Name
    RAN GTPase 3
    Primary source
    TAIR:AT5G55190
    Locus tag
    AT5G55190
    See related
    Araport:AT5G55190
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATRAN3; MCO15.14; MCO15_14; RAN GTPase 3; RAN GTPASE 3
    Summary
    A member of RAN GTPase gene family. Encodes a small soluble GTP-binding protein. Likely to be involved in nuclear translocation of proteins. May also be involved in cell cycle progression.
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    Genomic context

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    See RAN3 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    8
    Sequence:
    Chromosome: 5; NC_003076.8 (22392063..22394185)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene small ubiquitin-like modifier 3 Neighboring gene O-Glycosyl hydrolases family 17 protein Neighboring gene Co-chaperone GrpE family protein Neighboring gene uncharacterized protein Neighboring gene trigger factor type chaperone family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Interaction between methyl CpG-binding protein and ran GTPase during cell division in tobacco cultured cells. Yano A, et al. Ann Bot, 2006 Dec. PMID 17008347, Free PMC Article
    2. Properties of a tobacco DNA methyltransferase, NtMET1 and its involvement in chromatin movement during cell division. Kim HJ, et al. Ann Bot, 2007 May. PMID 17337479, Free PMC Article
    3. Characterization of proteins that interact with the GTP-bound form of the regulatory GTPase Ran in Arabidopsis. Haizel T, et al. Plant J, 1997 Jan. PMID 9025305
    4. An Arabidopsis homolog of importin β1 is required for ABA response and drought tolerance. Luo Y, et al. Plant J, 2013 Aug. PMID 23582042
    5. Isolation and identification of ubiquitin-related proteins from Arabidopsis seedlings. Igawa T, et al. J Exp Bot, 2009. PMID 19429840, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. This study showed that AtMBD5 becomes localized to the vicinity of chromosomes with the aid of AtRAN3 during cell division.
      Title: Interaction between methyl CpG-binding protein and ran GTPase during cell division in tobacco cultured cells.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_124901.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables GTP binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables GTPase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables mRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within protein import into nucleus TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus HDA PubMed 
    NOT located_in cytosol RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    located_in intracellular anatomical structure TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plasmodesma HDA PubMed 
    located_in plastid HDA PubMed 

    General protein information

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    Preferred Names
    RAN GTPase 3
    NP_200330.1
    • RAN GTPase 3 (RAN3); FUNCTIONS IN: protein binding, GTP binding, GTPase activity; INVOLVED IN: protein import into nucleus; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Ran GTPase (InterPro:IPR002041), Small GTP-binding protein (InterPro:IPR005225), Ras (InterPro:IPR013753); BEST Arabidopsis thaliana protein match is: RAS-related nuclear protein-1 (TAIR:AT5G20010.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      22392063..22394185
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_124901.5 → NP_200330.1  RAN GTPase 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_200330.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O04148, O04664, O22495, Q8H156
      UniProtKB/TrEMBL
      A0A178UD71, A0A5S9YFB8, A0A654GBD5
      Conserved Domains (1) summary
      PLN03071
      Location:1 → 218
      PLN03071; GTP-binding nuclear protein Ran; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8H156.2

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