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    GNC GATA type zinc finger transcription factor family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 835788, updated on 18-Sep-2024

    Summary

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    Official Symbol
    GNC
    Official Full Name
    GATA type zinc finger transcription factor family protein
    Primary source
    TAIR:AT5G56860
    Locus tag
    AT5G56860
    See related
    Araport:AT5G56860
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    carbon metabolism-involved; GATA; GATA TRANSCRIPTION FACTOR 21; GATA21; MPI10.2; MPI10_2; nitrate-inducible
    Summary
    Encodes a member of the GATA factor family of zinc finger transcription factors. Modulate chlorophyll biosynthesis and glutamate synthase (GLU1/Fd-GOGAT) expression.
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    Genomic context

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    See GNC in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    3
    Sequence:
    Chromosome: 5; NC_003076.8 (22989216..22991530, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene myb-like transcription factor family protein Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The chromatin remodelling ATPase BRAHMA interacts with GATA-family transcription factor GNC to regulate flowering time in Arabidopsis. Yang J, et al. J Exp Bot, 2022 Jan 27. PMID 34545936
    2. Coordination of Chloroplast Development through the Action of the GNC and GLK Transcription Factor Families. Zubo YO, et al. Plant Physiol, 2018 Sep. PMID 30002259, Free PMC Article
    3. Functional characterization of the GATA transcription factors GNC and CGA1 reveals their key role in chloroplast development, growth, and division in Arabidopsis. Chiang YH, et al. Plant Physiol, 2012 Sep. PMID 22811435, Free PMC Article
    4. GNC and CGA1 modulate chlorophyll biosynthesis and glutamate synthase (GLU1/Fd-GOGAT) expression in Arabidopsis. Hudson D, et al. PLoS One, 2011. PMID 22102866, Free PMC Article
    5. The GATA-type transcription factors GNC and GNL/CGA1 repress gibberellin signaling downstream from DELLA proteins and PHYTOCHROME-INTERACTING FACTORS. Richter R, et al. Genes Dev, 2010 Sep 15. PMID 20844019, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The chromatin remodelling ATPase BRAHMA interacts with GATA-family transcription factor GNC to regulate flowering time in Arabidopsis.
      Title: The chromatin remodelling ATPase BRAHMA interacts with GATA-family transcription factor GNC to regulate flowering time in Arabidopsis.
    2. Results indicate key regulatory features of the GATA NITRATE-INDUCIBLE CARBON-METABOLISM-INVOLVED (GNC) and GOLDEN TWO-LIKE (GLK2) transcription factor families that contribute to the control of chloroplast biogenesis and photosynthetic activity.
      Title: Coordination of Chloroplast Development through the Action of the GNC and GLK Transcription Factor Families.
    3. a cross-repressive interaction of GNC and GNL on the one side and SOC1 on the other in the control of flowering time, greening, and cold tolerance
      Title: Cross-repressive interactions between SOC1 and the GATAs GNC and GNL/CGA1 in the control of greening, cold tolerance, and flowering time in Arabidopsis.
    4. Data indicate that CARBON-METABOLISM INVOLVED (GNC) and GNC-LIKE (GNL)/CYTOKININ-RESPONSIVE GATA FACTOR1 (CGA1) expression is repressed by AUXIN RESPONSE FACTO ARF2 and ARF7.
      Title: Convergence of auxin and gibberellin signaling on the regulation of the GATA transcription factors GNC and GNL in Arabidopsis thaliana.
    5. GNC and CGA1 regulate chlorophyll production, and positively regulate chloroplast growth in the hypocotyl. GNC overexpression promotes chloroplast biogenesis in the root.
      Title: Functional characterization of the GATA transcription factors GNC and CGA1 reveals their key role in chloroplast development, growth, and division in Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_125069.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables transcription cis-regulatory region binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in chloroplast elongation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in chloroplast organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within circadian rhythm IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in cytokinin-activated signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within gibberellic acid mediated signaling pathway IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within glucose mediated signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within negative regulation of flower development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in negative regulation of gibberellic acid mediated signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within negative regulation of seed germination IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in plant organ senescence IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of chlorophyll biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of DNA-templated transcription IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of carbohydrate utilization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of chlorophyll biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of gene expression IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in regulation of photoperiodism, flowering IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of seed development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of seed germination IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in response to auxin IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to cytokinin IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to gibberellin IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to light stimulus IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    GATA type zinc finger transcription factor family protein
    NP_200497.1
    • GATA, nitrate-inducible, carbon metabolism-involved (GNC); CONTAINS InterPro DOMAIN/s: Zinc finger, NHR/GATA-type (InterPro:IPR013088), Zinc finger, GATA-type (InterPro:IPR000679); BEST Arabidopsis thaliana protein match is: cytokinin-responsive gata factor 1 (TAIR:AT4G26150.1); Has 1952 Blast hits to 1890 proteins in 209 species: Archae - 0; Bacteria - 2; Metazoa - 234; Fungi - 682; Plants - 707; Viruses - 0; Other Eukaryotes - 327 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      22989216..22991530 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_125069.3 → NP_200497.1  GATA type zinc finger transcription factor family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_200497.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q5HZ36, Q8VZC1, Q9LV39
      UniProtKB/TrEMBL
      A0A5S9YEX3, A0A654GBT4, Q1EBW4
      Conserved Domains (2) summary
      smart00401
      Location:227 → 263
      ZnF_GATA; zinc finger binding to DNA consensus sequence [AT]GATA[AG]
      COG5641
      Location:180 → 259
      GAT1; GATA Zn-finger-containing transcription factor [Transcription]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5HZ36.2

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