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    SYN4 sister chromatid cohesion 1 protein 4 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 831487, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SYN4
    Official Full Name
    sister chromatid cohesion 1 protein 4
    Primary source
    TAIR:AT5G16270
    Locus tag
    AT5G16270
    See related
    Araport:AT5G16270
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS HOMOLOG OF RAD21 3; ATRAD21.3; sister chromatid cohesion 1 protein 4; T21H19.190; T21H19_190
    Summary
    Encodes a SCC1/REC8 ortholog that may be involved in mitosis and may represent a mitotic cohesin.
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    Genomic context

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    See SYN4 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    16
    Sequence:
    Chromosome: 5; NC_003076.8 (5316197..5322700)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene RNA binding (RRM/RBD/RNP motifs) family protein Neighboring gene Tetratricopeptide repeat (TPR)-like superfamily protein Neighboring gene F-box family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The AtRAD21.1 and AtRAD21.3 Arabidopsis cohesins play a synergistic role in somatic DNA double strand break damage repair. da Costa-Nunes JA, et al. BMC Plant Biol, 2014 Dec 16. PMID 25511710, Free PMC Article
    2. Cohesin gene defects may impair sister chromatid alignment and genome stability in Arabidopsis thaliana. Schubert V, et al. Chromosoma, 2009 Oct. PMID 19533160
    3. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article
    4. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_121632.4

    Gene Ontology Provided by TAIR

    Process Evidence Code Pubs
    involved_in centromeric sister chromatid cohesion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within double-strand break repair IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within sister chromatid cohesion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of cohesin complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    sister chromatid cohesion 1 protein 4
    NP_197131.2
    • sister chromatid cohesion 1 protein 4 (SYN4); FUNCTIONS IN: molecular_function unknown; INVOLVED IN: sister chromatid cohesion; LOCATED IN: nuclear chromosome; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Rad21/Rec8 like protein, C-terminal (InterPro:IPR006909), Rad21/Rec8 like protein, N-terminal (InterPro:IPR006910); BEST Arabidopsis thaliana protein match is: Rad21/Rec8-like family protein (TAIR:AT3G59550.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      5316197..5322700
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_121632.4 → NP_197131.2  sister chromatid cohesion 1 protein 4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_197131.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8W1Y0, Q940G1, Q9LF01
      UniProtKB/TrEMBL
      A0A5S9Y4L1
      Conserved Domains (2) summary
      pfam04824
      Location:972 → 1026
      Rad21_Rec8; Conserved region of Rad21 / Rec8 like protein
      pfam04825
      Location:1 → 104
      Rad21_Rec8_N; N terminus of Rad21 / Rec8 like protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8W1Y0.1

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