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    LEJ2 Cystathionine beta-synthase (CBS) family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 829844, updated on 18-Sep-2024

    Summary

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    Official Symbol
    LEJ2
    Official Full Name
    Cystathionine beta-synthase (CBS) family protein
    Primary source
    TAIR:AT4G36910
    Locus tag
    AT4G36910
    See related
    Araport:AT4G36910
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AP22.61; AP22_61; CBS domain containing protein 1; CBSX1; CDCP2; CYSTATHIONE [BETA]-SYNTHASE DOMAIN-CONTAINING PROTEIN 2; LOSS OF THE TIMING OF ET AND JA BIOSYNTHESIS 2
    Summary
    Encodes a single cystathionine beta-synthase domain-containing protein. Modulates development by regulating the thioredoxin system.
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    Genomic context

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    See LEJ2 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    8
    Sequence:
    Chromosome: 4; NC_003075.7 (17390626..17393479, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Single cystathionine β-synthase domain-containing proteins modulate development by regulating the thioredoxin system in Arabidopsis. Yoo KS, et al. Plant Cell, 2011 Oct. PMID 22021414, Free PMC Article
    2. Sorting signals, N-terminal modifications and abundance of the chloroplast proteome. Zybailov B, et al. PLoS One, 2008 Apr 23. PMID 18431481, Free PMC Article
    3. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article
    4. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Two CBS domain-containing proteins, CBSX1 and CBSX2, are localized to the chloroplast, where they activate all four thioredoxins in the ferredoxin-thioredoxin system in Arabidopsis thaliana.
      Title: Single cystathionine β-synthase domain-containing proteins modulate development by regulating the thioredoxin system in Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_119855.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell redox homeostasis IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Cystathionine beta-synthase (CBS) family protein
    NP_195409.1
    • LOSS OF THE TIMING OF ET AND JA BIOSYNTHESIS 2 (LEJ2); FUNCTIONS IN: molecular_function unknown; INVOLVED IN: biological_process unknown; LOCATED IN: chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Cystathionine beta-synthase, core (InterPro:IPR000644); BEST Arabidopsis thaliana protein match is: Cystathionine beta-synthase (CBS) family protein (TAIR:AT4G34120.1); Has 8411 Blast hits to 7757 proteins in 1885 species: Archae - 1245; Bacteria - 5956; Metazoa - 278; Fungi - 143; Plants - 147; Viruses - 0; Other Eukaryotes - 642 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      17390626..17393479 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_119855.4 → NP_195409.1  Cystathionine beta-synthase (CBS) family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_195409.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O23193
      UniProtKB/TrEMBL
      A0A654FW62
      Conserved Domains (2) summary
      COG0517
      Location:77 → 222
      CBS; CBS domain [Signal transduction mechanisms]
      cd02205
      Location:85 → 224
      CBS_pair; The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O23193.2

    Gene LinkOut

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