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    CBL6 calcineurin B-like protein 6 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 827330, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CBL6
    Official Full Name
    calcineurin B-like protein 6
    Primary source
    TAIR:AT4G16350
    Locus tag
    AT4G16350
    See related
    Araport:AT4G16350
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    calcineurin B-like protein 6; DL4205C; FCAALL.89; SCABP2; SOS3-LIKE CALCIUM BINDING PROTEIN 2
    Summary
    Calcium sensor protein. Binds CIPK14.
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    Genomic context

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    See CBL6 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    8
    Sequence:
    Chromosome: 4; NC_003075.7 (9242274..9243912, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene LSD1-like 3 Neighboring gene 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily protein Neighboring gene guanyl-nucleotide exchange factors;GTPase binding;GTP binding protein Neighboring gene ncRNA Neighboring gene SNF1-related protein kinase regulatory subunit beta-2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. N-terminal S-acylation facilitates tonoplast targeting of the calcium sensor CBL6. Zhang C, et al. FEBS Lett, 2017 Nov. PMID 29023681
    2. Calcineurin B-like 3 calcium sensor associates with and inhibits 5'-methylthioadenosine nucleosidase 2 in Arabidopsis. Ok SH, et al. Plant Sci, 2015 Sep. PMID 26259190
    3. A protein kinase, calcineurin B-like protein-interacting protein Kinase9, interacts with calcium sensor calcineurin B-like Protein3 and regulates potassium homeostasis under low-potassium stress in Arabidopsis. Liu LL, et al. Plant Physiol, 2013 Jan. PMID 23109687, Free PMC Article
    4. The NAF domain defines a novel protein-protein interaction module conserved in Ca2+-regulated kinases. Albrecht V, et al. EMBO J, 2001 Mar 1. PMID 11230129, Free PMC Article
    5. Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling. McBride Z, et al. Mol Cell Proteomics, 2017 Nov. PMID 28887381, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_117730.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables calcium ion binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables kinase binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within calcium-mediated signaling ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol HDA PubMed 
    located_in intracellular anatomical structure ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    calcineurin B-like protein 6
    NP_567492.1
    • calcineurin B-like protein 6 (CBL6); FUNCTIONS IN: calcium ion binding; INVOLVED IN: calcium-mediated signaling; LOCATED IN: endomembrane system; EXPRESSED IN: sepal, male gametophyte, root, carpel, stamen; EXPRESSED DURING: 4 anthesis; CONTAINS InterPro DOMAIN/s: Recoverin (InterPro:IPR001125), EF-HAND 2 (InterPro:IPR018249), Calcineurin B protein (InterPro:IPR015757), EF-hand-like domain (InterPro:IPR011992), Calcium-binding EF-hand (InterPro:IPR002048); BEST Arabidopsis thaliana protein match is: calcineurin B-like 3 (TAIR:AT4G26570.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      9242274..9243912 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001341098.1 → NP_001328805.1  calcineurin B-like protein 6 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O23480, Q9C5P6, Q9FVF2
      UniProtKB/TrEMBL
      A0A178V1R7, A0A654FPX1
      Conserved Domains (1) summary
      COG5126
      Location:38 → 192
      FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]

    2. NM_117730.3 → NP_567492.1  calcineurin B-like protein 6 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_567492.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O23480, Q9C5P6, Q9FVF2
      UniProtKB/TrEMBL
      A0A178V1R7, A0A654FPX1
      Conserved Domains (1) summary
      COG5126
      Location:38 → 192
      FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9C5P6.2

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