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    PTEN1 Calcium/lipid-binding (CaLB) phosphatase [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 833936, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PTEN1
    Official Full Name
    Calcium/lipid-binding (CaLB) phosphatase
    Primary source
    TAIR:AT5G39400
    Locus tag
    AT5G39400
    See related
    Araport:AT5G39400
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATPTEN1; MUL8.8; MUL8_8; Phosphatase and TENsin homolog deleted on chromosome ten 1
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    Genomic context

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    See PTEN1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    8
    Sequence:
    Chromosome: 5; NC_003076.8 (15766037..15768354)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Plant calmodulin-binding protein-like protein Neighboring gene Leucine-rich repeat protein kinase family protein Neighboring gene Saccharopine dehydrogenase Neighboring gene ncRNA Neighboring gene CDC2C

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A tumor suppressor homolog, AtPTEN1, is essential for pollen development in Arabidopsis. Gupta R, et al. Plant Cell, 2002 Oct. PMID 12368500, Free PMC Article
    2. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article
    3. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_123302.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables phosphatase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables phosphatidylinositol phosphate phosphatase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein tyrosine phosphatase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within dephosphorylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in phosphatidylinositol dephosphorylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within pollen development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Calcium/lipid-binding (CaLB) phosphatase
    NP_198756.2
    • PTEN1; CONTAINS InterPro DOMAIN/s: Protein-tyrosine phosphatase, active site (InterPro:IPR016130), Phosphatase tensin type (InterPro:IPR014019), Dual specificity phosphatase, catalytic domain (InterPro:IPR000340), C2 calcium/lipid-binding domain, CaLB (InterPro:IPR008973), Tensin phosphatase, C2 domain (InterPro:IPR014020); BEST Arabidopsis thaliana protein match is: PTEN 2 (TAIR:AT3G19420.1); Has 1458 Blast hits to 1454 proteins in 210 species: Archae - 8; Bacteria - 27; Metazoa - 855; Fungi - 236; Plants - 75; Viruses - 0; Other Eukaryotes - 257 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      15766037..15768354
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_123302.4 → NP_198756.2  Calcium/lipid-binding (CaLB) phosphatase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_198756.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FLZ5
      UniProtKB/TrEMBL
      A0A178UKD4, A0A5S9Y9J0, A0A654G6D9
      Conserved Domains (2) summary
      cd14509
      Location:52 → 207
      PTP_PTEN; protein tyrosine phosphatase-like catalytic domain of phosphatase and tensin homolog
      pfam10409
      Location:327 → 395
      PTEN_C2; C2 domain of PTEN tumor-suppressor protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FLZ5.1

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