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    TUB4 tubulin beta chain 4 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 834459, updated on 18-Sep-2024

    Summary

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    Official Symbol
    TUB4
    Official Full Name
    tubulin beta chain 4
    Primary source
    TAIR:AT5G44340
    Locus tag
    AT5G44340
    See related
    Araport:AT5G44340
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    K9L2.12; K9L2_12; tubulin beta chain 4
    Summary
    beta tubulin gene
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    Genomic context

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    See TUB4 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    3
    Sequence:
    Chromosome: 5; NC_003076.8 (17859136..17861150, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Neighboring gene Tetratricopeptide repeat (TPR)-like superfamily protein Neighboring gene F-box associated ubiquitination effector family protein Neighboring gene ethylene-responsive nuclear protein-like protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Phosducin-Like Protein 3 is required for microtubule-dependent steps of cell division but not for meristem growth in Arabidopsis. Castellano MM, et al. Plant Cell, 2008 Apr. PMID 18390592, Free PMC Article
    2. The small genome of Arabidopsis contains at least nine expressed beta-tubulin genes. Snustad DP, et al. Plant Cell, 1992 May. PMID 1498609, Free PMC Article
    3. Arabidopsis scaffold protein RACK1A interacts with diverse environmental stress and photosynthesis related proteins. Kundu N, et al. Plant Signal Behav, 2013 May. PMID 23435172, Free PMC Article
    4. Identification and dynamics of Arabidopsis adaptor protein-2 complex and its involvement in floral organ development. Yamaoka S, et al. Plant Cell, 2013 Aug. PMID 23975897, Free PMC Article
    5. Identification of ubiquitinated proteins in Arabidopsis. Manzano C, et al. Plant Mol Biol, 2008 Sep. PMID 18535787

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_123801.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables mRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables structural constituent of cytoskeleton ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in microtubule-based process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in Golgi apparatus HDA PubMed 
    located_in chloroplast stroma HDA PubMed 
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytosol HDA PubMed 
    located_in plant-type cell wall HDA PubMed 
    located_in plasma membrane HDA PubMed 
    located_in plasmodesma HDA PubMed 
    located_in plastid HDA PubMed 
    part_of tubulin complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    tubulin beta chain 4
    NP_199247.1
    • tubulin beta chain 4 (TUB4); FUNCTIONS IN: structural constituent of cytoskeleton; INVOLVED IN: microtubule-based process, protein polymerization, microtubule-based movement; LOCATED IN: tubulin complex, cell wall; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: Beta tubulin (InterPro:IPR002453), Tubulin (InterPro:IPR000217), Tubulin/FtsZ, GTPase domain (InterPro:IPR003008), Tubulin/FtsZ, N-terminal (InterPro:IPR019746), Tubulin/FtsZ, C-terminal (InterPro:IPR008280), Beta tubulin, autoregulation binding site (InterPro:IPR013838), Tubulin, conserved site (InterPro:IPR017975), Tubulin/FtsZ, 2-layer sandwich domain (InterPro:IPR018316); BEST Arabidopsis thaliana protein match is: tubulin beta-9 chain (TAIR:AT4G20890.1); Has 23619 Blast hits to 23523 proteins in 4869 species: Archae - 36; Bacteria - 51; Metazoa - 4471; Fungi - 14157; Plants - 1545; Viruses - 0; Other Eukaryotes - 3359 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      17859136..17861150 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_123801.2 → NP_199247.1  tubulin beta chain 4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_199247.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P24636, Q9FKV4
      UniProtKB/TrEMBL
      A0A178UGW7, A0A5S9YB77, Q8GY15
      Conserved Domains (1) summary
      PLN00220
      Location:1 → 431
      PLN00220; tubulin beta chain; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P24636.2

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