MATE efflux family protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Full Name: MATE efflux family protein
Primary source: TAIR:AT5G52050
Locus tag: AT5G52050
See related: Araport:AT5G52050
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: AtDTX50; Detoxification Efflux Carrier 50; DTX50; MSG15.13; MSG15_13
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Genomic context

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See in Genome Data Viewer

Location:: chromosome: 5

Exon count:: 1

Sequence:: Chromosome: 5; NC_003076.8 (21138703..21140876)

Chromosome 5 - NC_003076.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

AtDTX50, functions as an abscissic acid efflux transporter. [AtDTX50]
Title: A DTX/MATE-type transporter facilitates abscisic acid efflux and modulates ABA sensitivity and drought tolerance in Arabidopsis.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_124584.3

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables abscisic acid transmembrane transporter activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables antiporter activity	IEA Inferred from Electronic Annotation more info
enables xenobiotic transmembrane transporter activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in abscisic acid transport	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of response to water deprivation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in response to abscisic acid	IEP Inferred from Expression Pattern more info	PubMed
involved_in root morphogenesis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in xenobiotic detoxification by transmembrane export across the plasma membrane	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in chloroplast	ISM Inferred from Sequence Model more info
located_in late endosome	IDA Inferred from Direct Assay more info	PubMed
located_in plasma membrane	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: MATE efflux family protein

NP_200018.1

MATE efflux family protein; FUNCTIONS IN: antiporter activity, drug transmembrane transporter activity; INVOLVED IN: drug transmembrane transport, transmembrane transport; LOCATED IN: membrane; EXPRESSED IN: 7 plant structures; EXPRESSED DURING: 7 growth stages; CONTAINS InterPro DOMAIN/s: Multi antimicrobial extrusion protein MatE (InterPro:IPR002528); BEST Arabidopsis thaliana protein match is: MATE efflux family protein (TAIR:AT4G23030.1); Has 10796 Blast hits to 10712 proteins in 2003 species: Archae - 245; Bacteria - 7617; Metazoa - 145; Fungi - 324; Plants - 1294; Viruses - 0; Other Eukaryotes - 1171 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003076.8 Reference assembly

Range

21138703..21140876

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_124584.3 → NP_200018.1 MATE efflux family protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_200018.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q7FLS2, Q9FJ87

UniProtKB/TrEMBL

A0A178UM67, A0A5S9YDD0, A0A654GAD7

Conserved Domains (1) summary

cd13132
Location:35 → 477

MATE_eukaryotic; Eukaryotic members of the multidrug and toxic compound extrusion (MATE) family