IAA1 indole-3-acetic acid inducible [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: IAA1
Official Full Name: indole-3-acetic acid inducible
Primary source: TAIR:AT4G14560
Locus tag: AT4G14560
See related: Araport:AT4G14560
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: AUX/IAA PROTEIN 1; AUXIN RESISTANT 5; AXR5; DL3320W; FCAALL.409; indole-3-acetic acid inducible; indole-3-acetic acid inducible 1
Summary: auxin (indole-3-acetic acid) induced gene (IAA1) encoding a short-lived nuclear-localized transcriptional regulator protein.
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Chromosome 4 - NC_003075.7 Genomic Context describing neighboring genes

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Lysine-less IAA1 was ubiquitinated and rapidly degraded in vivo.
Title: Lysine Residues Are Not Required for Proteasome-Mediated Proteolysis of the Auxin/Indole Acidic Acid Protein IAA1.
These data suggest that increased IAA1-luciferase fusion protein half-life in top6b-7 probably results from a combination of both lower endogenous IAA levels and reduced sensitivity to auxin.
Title: A genetic screen for mutants defective in IAA1-LUC degradation in Arabidopsis thaliana reveals an important requirement for TOPOISOMERASE6B in auxin physiology.
Iaa1-regulated auxin-response genes are controlled by ARFs to different extents.
Title: Genome-wide analysis of the auxin-responsive transcriptome downstream of iaa1 and its expression analysis reveal the diversity and complexity of auxin-regulated gene expression.
IAA1 might be involved in cell elongation as well as in cell division in the aerial parts of Arabidopsis plants.
Title: Overexpression of IAA1 with domain II mutation impairs cell elongation and cell division in inflorescences and leaves of Arabidopsis.
The molecular cloning of AXR5 revealed that the gene encodes the IAA1 protein, a member of the Aux/IAA family of proteins.
Title: The IAA1 protein is encoded by AXR5 and is a substrate of SCF(TIR1).

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

NM_117536.4

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables identical protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables transcription cis-regulatory region binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within response to auxin	IEP Inferred from Expression Pattern more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	ISM Inferred from Sequence Model more info

NP_193192.1

indole-3-acetic acid inducible (IAA1); CONTAINS InterPro DOMAIN/s: Aux/IAA-ARF-dimerisation (InterPro:IPR011525), AUX/IAA protein (InterPro:IPR003311); BEST Arabidopsis thaliana protein match is: indole-3-acetic acid inducible 2 (TAIR:AT3G23030.1); Has 1898 Blast hits to 1895 proteins in 83 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 2; Plants - 1895; Viruses - 0; Other Eukaryotes - 1 (source: NCBI BLink).

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