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    ABCG34 pleiotropic drug resistance 6 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 818211, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ABCG34
    Official Full Name
    pleiotropic drug resistance 6
    Primary source
    TAIR:AT2G36380
    Locus tag
    AT2G36380
    See related
    Araport:AT2G36380
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATP-binding cassette G34; ATPDR6; F1O11.1; F1O11_1; PDR6; pleiotropic drug resistance 6; PLEIOTROPIC DRUG RESISTANCE 6
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    Genomic context

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    See ABCG34 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    19
    Sequence:
    Chromosome: 2; NC_003071.7 (15257418..15263808)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene ubiquitin-protein ligase Neighboring gene ncRNA Neighboring gene starch branching enzyme 2.1 Neighboring gene growth-regulating factor 3 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis ABCG34 contributes to defense against necrotrophic pathogens by mediating the secretion of camalexin. Khare D, et al. Proc Natl Acad Sci U S A, 2017 Jul 11. PMID 28652324, Free PMC Article
    2. AGC kinases OXI1 and AGC2-2 regulate camalexin secretion and disease resistance by phosphorylating transporter PDR6. Han J, et al. Plant Physiol, 2024 Jun 28. PMID 38535832
    3. Mapping the Arabidopsis organelle proteome. Dunkley TP, et al. Proc Natl Acad Sci U S A, 2006 Apr 25. PMID 16618929, Free PMC Article
    4. Novel Aquaporin Regulatory Mechanisms Revealed by Interactomics. Bellati J, et al. Mol Cell Proteomics, 2016 Nov. PMID 27609422, Free PMC Article
    5. Putative glycosyltransferases and other plant Golgi apparatus proteins are revealed by LOPIT proteomics. Nikolovski N, et al. Plant Physiol, 2012 Oct. PMID 22923678, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. AGC kinases OXI1 and AGC2-2 regulate camalexin secretion and disease resistance by phosphorylating transporter PDR6.
      Title: AGC kinases OXI1 and AGC2-2 regulate camalexin secretion and disease resistance by phosphorylating transporter PDR6.
    2. AtABCG34 mediates camalexin secretion to the leaf surface and thereby prevents Abrassicicola infection
      Title: Arabidopsis ABCG34 contributes to defense against necrotrophic pathogens by mediating the secretion of camalexin.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_129195.6

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ABC-type transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATPase-coupled transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plasma membrane HDA PubMed 

    General protein information

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    Preferred Names
    pleiotropic drug resistance 6
    NP_181179.2
    • pleiotropic drug resistance 6 (PDR6); FUNCTIONS IN: ATPase activity, coupled to transmembrane movement of substances; LOCATED IN: plasma membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ABC transporter-like (InterPro:IPR003439), Plant PDR ABC transporter associated (InterPro:IPR013581), ABC-2 type transporter (InterPro:IPR013525); BEST Arabidopsis thaliana protein match is: pleiotropic drug resistance 11 (TAIR:AT1G66950.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      15257418..15263808
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_129195.6 → NP_181179.2  pleiotropic drug resistance 6 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_181179.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q56YS3, Q7PC87, Q9SJR6
      UniProtKB/TrEMBL
      A0A178VWW9, A0A5S9X4N1
      Conserved Domains (1) summary
      PLN03140
      Location:11 → 1453
      PLN03140; ABC transporter G family member; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7PC87.1

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