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    SHN1 Integrase-type DNA-binding superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 838105, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SHN1
    Official Full Name
    Integrase-type DNA-binding superfamily protein
    Primary source
    TAIR:AT1G15360
    Locus tag
    AT1G15360
    See related
    Araport:AT1G15360
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtSHN1; F9L1.31; F9L1_31; SHINE 1; WAX INDUCER 1; WIN1
    Summary
    Encodes a member of the ERF (ethylene response factor) subfamily B-6 of ERF/AP2 transcription factor family. The protein contains one AP2 domain. There are 12 members in this subfamily including RAP2.11. This gene is involved in wax biosynthesis. Over-expression of the gene results in glossy leaf phenotype and increased drought tolerance. Two closely related genes, AT5G25390 and AT5G11190 have similar phenotypes when over-expressed. Strong expression levels in flowers. Binds to the promoter of LACS2.
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    Genomic context

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    See SHN1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    2
    Sequence:
    Chromosome: 1; NC_003070.9 (5283268..5284736)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene DUF4050 family protein Neighboring gene miscRNA Neighboring gene SNARE-like superfamily protein Neighboring gene Lactoylglutathione lyase / glyoxalase I family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Induced accumulation of cuticular waxes enhances drought tolerance in Arabidopsis by changes in development of stomata. Yang J, et al. Plant Physiol Biochem, 2011 Dec. PMID 22078383
    2. The transcription factor WIN1/SHN1 regulates Cutin biosynthesis in Arabidopsis thaliana. Kannangara R, et al. Plant Cell, 2007 Apr. PMID 17449808, Free PMC Article
    3. The SHINE clade of AP2 domain transcription factors activates wax biosynthesis, alters cuticle properties, and confers drought tolerance when overexpressed in Arabidopsis. Aharoni A, et al. Plant Cell, 2004 Sep. PMID 15319479, Free PMC Article
    4. Overexpression of AtSHN1/WIN1 provokes unique defense responses. Sela D, et al. PLoS One, 2013. PMID 23922943, Free PMC Article
    5. MIXTA-like transcription factors and WAX INDUCER1/SHINE1 coordinately regulate cuticle development in Arabidopsis and Torenia fournieri. Oshima Y, et al. Plant Cell, 2013 May. PMID 23709630, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Overexpression of AtSHN1/WIN1 provokes unique defense responses.
      Title: Overexpression of AtSHN1/WIN1 provokes unique defense responses.
    2. Data indicate that the MIXTA-like MYB transcription factors MYB106 and MYB16, which regulate epidermal cell morphology, also regulate cuticle development coordinately with WIN1/SHN1.
      Title: MIXTA-like transcription factors and WAX INDUCER1/SHINE1 coordinately regulate cuticle development in Arabidopsis and Torenia fournieri.
    3. when expression of the WIN1/SHN1 gene was induced there was increased expression of genes involved in wax development...
      Title: Induced accumulation of cuticular waxes enhances drought tolerance in Arabidopsis by changes in development of stomata.
    4. Silencing SHINE clade genes (SHN1/SHN2/SHN3) reduces flower cutin load and modifies petal cell wall structure.
      Title: SHINE transcription factors act redundantly to pattern the archetypal surface of Arabidopsis flower organs.
    5. Work identified WIN1, a putative acetylornithine transaminase, as Pseudomonas syringae HopW1-1-interacting plant proteins.
      Title: Arabidopsis proteins important for modulating defense responses to Pseudomonas syringae that secrete HopW1-1.
    6. At least one of the cutin pathway genes, which encodes long-chain acyl-CoA synthetase LACS2, is likely to be directly targeted by WIN1.
      Title: The transcription factor WIN1/SHN1 regulates Cutin biosynthesis in Arabidopsis thaliana.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001332163.1
    NM_101405.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables sequence-specific DNA binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cutin biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within ethylene-activated signaling pathway TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within response to water deprivation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within wax metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in intracellular anatomical structure TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Integrase-type DNA-binding superfamily protein
    NP_172988.1
    • SHINE 1 (SHN1); CONTAINS InterPro DOMAIN/s: DNA-binding, integrase-type (InterPro:IPR016177), Pathogenesis-related transcriptional factor/ERF, DNA-binding (InterPro:IPR001471); BEST Arabidopsis thaliana protein match is: Integrase-type DNA-binding superfamily protein (TAIR:AT5G25390.2); Has 5918 Blast hits to 5765 proteins in 265 species: Archae - 0; Bacteria - 6; Metazoa - 9; Fungi - 23; Plants - 5843; Viruses - 2; Other Eukaryotes - 35 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      5283268..5284736
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_101405.4 → NP_172988.1  Integrase-type DNA-binding superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_172988.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8LDZ0, Q9XI33
      UniProtKB/TrEMBL
      A0A178WNC4, A0A5S9UIT0, A0A7G2DTX1
      Conserved Domains (1) summary
      smart00380
      Location:6 → 68
      AP2; DNA-binding domain in plant proteins such as APETALA2 and EREBPs

    2. NM_001332163.1 → NP_001322723.1  Integrase-type DNA-binding superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8LDZ0, Q9XI33
      UniProtKB/TrEMBL
      A0A178WNC4, A0A5S9UIT0, A0A7G2DTX1
      Conserved Domains (1) summary
      smart00380
      Location:6 → 68
      AP2; DNA-binding domain in plant proteins such as APETALA2 and EREBPs
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9XI33.1

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