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    Leucine-rich repeat transmembrane protein kinase [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 841778, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Leucine-rich repeat transmembrane protein kinase
    Primary source
    TAIR:AT1G53430
    Locus tag
    AT1G53430
    See related
    Araport:AT1G53430
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    T3F20.25; T3F20_25
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    24
    Sequence:
    Chromosome: 1; NC_003070.9 (19934987..19941185)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Ubiquitin domain-containing protein Neighboring gene tRNA-Cys Neighboring gene Leucine-rich repeat transmembrane protein kinase Neighboring gene Leucine-rich repeat transmembrane protein kinase Neighboring gene epstein-barr nuclear antigen Neighboring gene craniofacial development protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A brassinosteroid-signaling kinase interacts with multiple receptor-like kinases in Arabidopsis. Xu P, et al. Mol Plant, 2014 Feb. PMID 24051702, Free PMC Article
    2. An extracellular network of Arabidopsis leucine-rich repeat receptor kinases. Smakowska-Luzan E, et al. Nature, 2018 Jan 18. PMID 29320478, Free PMC Article
    3. A high content in lipid-modified peripheral proteins and integral receptor kinases features in the arabidopsis plasma membrane proteome. Marmagne A, et al. Mol Cell Proteomics, 2007 Nov. PMID 17644812
    4. Mapping the signaling network of BIN2 kinase using TurboID-mediated biotin labeling and phosphoproteomics. Kim TW, et al. Plant Cell, 2023 Mar 15. PMID 36660928, Free PMC Article
    5. Putative glycosyltransferases and other plant Golgi apparatus proteins are revealed by LOPIT proteomics. Nikolovski N, et al. Plant Physiol, 2012 Oct. PMID 22923678, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001124007.1
    NM_001333594.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables kinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus HDA PubMed 
    located_in plasma membrane HDA PubMed 
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Leucine-rich repeat transmembrane protein kinase
    NP_001117479.1
    • Leucine-rich repeat transmembrane protein kinase; FUNCTIONS IN: kinase activity; INVOLVED IN: protein amino acid phosphorylation; LOCATED IN: plasma membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Serine/threonine-protein kinase domain (InterPro:IPR002290), Leucine-rich repeat (InterPro:IPR001611), Serine-threonine/tyrosine-protein kinase (InterPro:IPR001245), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271), Malectin/receptor-like protein kinase (InterPro:IPR021720), Protein kinase, catalytic domain (InterPro:IPR000719), Leucine-rich repeat, typical subtype (InterPro:IPR003591), Tyrosine-protein kinase, catalytic domain (InterPro:IPR020635); BEST Arabidopsis thaliana protein match is: Leucine-rich repeat transmembrane protein kinase (TAIR:AT1G53440.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_001319214.1
    • Leucine-rich repeat transmembrane protein kinase; FUNCTIONS IN: kinase activity; INVOLVED IN: protein amino acid phosphorylation; LOCATED IN: plasma membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Serine/threonine-protein kinase domain (InterPro:IPR002290), Leucine-rich repeat (InterPro:IPR001611), Serine-threonine/tyrosine-protein kinase (InterPro:IPR001245), Serine/threonine-protein kinase, active site (InterPro:IPR008271), Protein kinase-like domain (InterPro:IPR011009), Protein kinase, catalytic domain (InterPro:IPR000719), Malectin/receptor-like protein kinase (InterPro:IPR021720), Leucine-rich repeat, typical subtype (InterPro:IPR003591), Tyrosine-protein kinase, catalytic domain (InterPro:IPR020635); BEST Arabidopsis thaliana protein match is: Leucine-rich repeat transmembrane protein kinase (TAIR:AT1G53440.1); Has 190391 Blast hits to 136728 proteins in 4882 species: Archae - 123; Bacteria - 17099; Metazoa - 53964; Fungi - 11192; Plants - 85200; Viruses - 463; Other Eukaryotes - 22350 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      19934987..19941185
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001333594.1 → NP_001319214.1  Leucine-rich repeat transmembrane protein kinase [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      C0LGG8, F4HRH3, Q8H7G0, Q9LPF9
      UniProtKB/TrEMBL
      A0A5S9WLG4
      Conserved Domains (3) summary
      PLN00113
      Location:62 → 941
      PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
      cd14066
      Location:675 → 942
      STKc_IRAK; Catalytic domain of the Serine/Threonine kinases, Interleukin-1 Receptor Associated Kinases and related STKs
      sd00033
      Location:92 → 115
      LRR_RI; leucine-rich repeat [structural motif]

    2. NM_001124007.1 → NP_001117479.1  Leucine-rich repeat transmembrane protein kinase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001117479.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9WLG4, F4HRH4
      Conserved Domains (5) summary
      smart00219
      Location:631 → 899
      TyrKc; Tyrosine kinase, catalytic domain
      COG4886
      Location:38 → 349
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      cd14066
      Location:634 → 901
      STKc_IRAK; Catalytic domain of the Serine/Threonine kinases, Interleukin-1 Receptor Associated Kinases and related STKs
      sd00033
      Location:83 → 104
      LRR_RI; leucine-rich repeat [structural motif]
      pfam11721
      Location:368 → 551
      Malectin; Di-glucose binding within endoplasmic reticulum
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    C0LGG8.1

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