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    DRB3 dsRNA-binding protein 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 822310, updated on 18-Sep-2024

    Summary

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    Official Symbol
    DRB3
    Official Full Name
    dsRNA-binding protein 3
    Primary source
    TAIR:AT3G26932
    Locus tag
    AT3G26932
    See related
    Araport:AT3G26932
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    dsRNA-binding protein 3; MQP17_7
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    Genomic context

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    See DRB3 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    3
    Sequence:
    Chromosome: 3; NC_003074.8 (9929996..9932249, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene Protein with RNI-like/FBD-like domain Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene DHHC-type zinc finger family protein Neighboring gene Protein kinase superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Double-stranded RNA-binding protein DRB3 negatively regulates anthocyanin biosynthesis by modulating PAP1 expression in Arabidopsis thaliana. Sawano H, et al. J Plant Res, 2017 Jan. PMID 27995376
    2. Arabidopsis double-stranded RNA binding protein DRB3 participates in methylation-mediated defense against geminiviruses. Raja P, et al. J Virol, 2014 Mar. PMID 24352449, Free PMC Article
    3. DRB2, DRB3 and DRB5 function in a non-canonical microRNA pathway in Arabidopsis thaliana. Eamens AL, et al. Plant Signal Behav, 2012 Oct 1. PMID 22902697, Free PMC Article
    4. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. DRB3 negatively regulates anthocyanin biosynthesis by modulating the level of PAP1 transcript.
      Title: Double-stranded RNA-binding protein DRB3 negatively regulates anthocyanin biosynthesis by modulating PAP1 expression in Arabidopsis thaliana.
    2. Unlike DRB2, DRB3 and DRB5 are not involved in the double stranded RNA processing stages of the microRNA (miRNA) biogenesis pathway, but are required to mediate RNA silencing of target genes of DRB2-associated miRNAs.
      Title: DRB2, DRB3 and DRB5 function in a non-canonical microRNA pathway in Arabidopsis thaliana.
    Submit: New GeneRIF Correction

    General gene information

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    NM_001035702.3
    NM_001338846.1
    NM_113606.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables double-stranded RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    dsRNA-binding protein 3
    NP_001030779.2
    • dsRNA-binding protein 3 (DRB3); FUNCTIONS IN: double-stranded RNA binding, RNA binding; INVOLVED IN: biological_process unknown; LOCATED IN: intracellular; EXPRESSED IN: 16 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: Double-stranded RNA-binding (InterPro:IPR001159), Double-stranded RNA-binding-like (InterPro:IPR014720); BEST Arabidopsis thaliana protein match is: dsRNA-binding protein 5 (TAIR:AT5G41070.1); Has 827 Blast hits to 709 proteins in 201 species: Archae - 0; Bacteria - 347; Metazoa - 113; Fungi - 0; Plants - 307; Viruses - 2; Other Eukaryotes - 58 (source: NCBI BLink).
    NP_189329.3
    • dsRNA-binding protein 3 (DRB3); FUNCTIONS IN: double-stranded RNA binding, RNA binding; INVOLVED IN: biological_process unknown; LOCATED IN: intracellular; EXPRESSED IN: 16 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: Double-stranded RNA-binding (InterPro:IPR001159), Double-stranded RNA-binding-like (InterPro:IPR014720); BEST Arabidopsis thaliana protein match is: dsRNA-binding protein 5 (TAIR:AT5G41070.1); Has 827 Blast hits to 709 proteins in 201 species: Archae - 0; Bacteria - 347; Metazoa - 113; Fungi - 0; Plants - 307; Viruses - 2; Other Eukaryotes - 58 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      9929996..9932249 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_113606.5 → NP_189329.3  dsRNA-binding protein 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_189329.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q2V3S2, Q9LJF5
      UniProtKB/TrEMBL
      A0A5S9XG08
      Conserved Domains (1) summary
      cd00048
      Location:2 → 68
      DSRM; Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III, ...

    2. NM_001035702.3 → NP_001030779.2  dsRNA-binding protein 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001030779.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q2V3S2, Q9LJF5
      UniProtKB/TrEMBL
      A0A5S9XG08
      Conserved Domains (1) summary
      cd00048
      Location:2 → 68
      DSRM; Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III, ...

    3. NM_001338846.1 → NP_001327581.1  dsRNA-binding protein 3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1I9LSR8
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LJF5.1

    Gene LinkOut

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