CAT2 catalase 2 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: CAT2
Official Full Name: catalase 2
Primary source: TAIR:AT4G35090
Locus tag: AT4G35090
See related: Araport:AT4G35090
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: CATALASE; catalase 2; T12J5.2
Summary: Encodes a peroxisomal catalase, highly expressed in bolts and leaves. mRNA expression patterns show circadian regulation with mRNA levels being high in the subjective early morning. Loss of function mutations have increased H2O2 levels and increased H2O2 sensitivity. Mutants accumulate more toxic ions yet show decreased sensitivity to Li+. This decreased sensitivity is most likely due to an insensitivity to ethylene. Note that in Queval et al. (2007) Plant Journal, 52(4):640, SALK_057998 is named as cat2-1, SALK_076998 is named as cat2-2; in Bueso et al. (2007) Plant Journal, 52(6):1052, SALK_076998 is named as cat2-1. TAIR has adopted the nomenclature consistent with that in Bueso et al. (2007) after consultation with the authors: SALK_076998 (cat2-1), SALK_057998 (cat2-2).
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Genomic context

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See CAT2 in Genome Data Viewer

Location:: chromosome: 4

Exon count:: 7

Sequence:: Chromosome: 4; NC_003075.7 (16700312..16703504, complement)

Chromosome 4 - NC_003075.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Reactive oxygen species coordinate the transcriptional responses to iron availability in Arabidopsis.
Title: Reactive oxygen species coordinate the transcriptional responses to iron availability in Arabidopsis.
CATALASE2 plays a crucial role in long-term heat tolerance of Arabidopsis thaliana.
Title: CATALASE2 plays a crucial role in long-term heat tolerance of Arabidopsis thaliana.
Chemical Genetics Approach Identifies Abnormal Inflorescence Meristem 1 as a Putative Target of a Novel Sulfonamide That Protects Catalase2-Deficient Arabidopsis against Photorespiratory Stress.
Title: Chemical Genetics Approach Identifies Abnormal Inflorescence Meristem 1 as a Putative Target of a Novel Sulfonamide That Protects Catalase2-Deficient Arabidopsis against Photorespiratory Stress.
Jasmonic acid promotes leaf senescence through MYC2-mediated repression of CATALASE2 expression in Arabidopsis.
Title: Jasmonic acid promotes leaf senescence through MYC2-mediated repression of CATALASE2 expression in Arabidopsis.
The Glycine- and Proline-Rich Protein AtGPRP3 Negatively Regulates Plant Growth in Arabidopsis.
Title: The Glycine- and Proline-Rich Protein AtGPRP3 Negatively Regulates Plant Growth in Arabidopsis.
The study also provides new insights that CaMBP may play a critical role in the cross talk of multiple signaling pathways in the context of plant defense processes.
Title: The Calmodulin-Binding Protein IQM1 Interacts with CATALASE2 to Affect Pathogen Defense.
essential role in growth and day length-dependent oxidative signalling
Title: Analysis of catalase mutants underscores the essential role of CATALASE2 for plant growth and day length-dependent oxidative signalling.
The cat1/2/3 triple mutants displayed severe redox disturbance and growth defects under physiological conditions compared with wild-type and the cat2/3 double mutants.
Title: The Arabidopsis catalase triple mutant reveals important roles of catalases and peroxisome-derived signaling in plant development.
CAT2 functions in early seedling growth by scavenging hydrogen peroxide and stimulating ACX2/3 activity.
Title: CATALASE2 functions for seedling postgerminative growth by scavenging H(2) O(2) and stimulating ACX2/3 activity in Arabidopsis.
SHORT-ROOT Deficiency Alleviates the Cell Death Phenotype of the Arabidopsis catalase2 Mutant under Photorespiration-Promoting Conditions
Title: SHORT-ROOT Deficiency Alleviates the Cell Death Phenotype of the Arabidopsis catalase2 Mutant under Photorespiration-Promoting Conditions.

Submit: New GeneRIF Correction See all GeneRIFs (25)

Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

MASC_STS16371 (e-PCR)
- UniSTS:258869

Homology

Orthologs from OrthoDB

NM_001036714.5

Supported by ESTs:

NM_001342324.1

Supported by ESTs:

NM_119675.4

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables catalase activity	IEA Inferred from Electronic Annotation more info
enables catalase activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables catalase activity	ISS Inferred from Sequence or Structural Similarity more info
enables cobalt ion binding	HDA more info	PubMed
enables heme binding	IEA Inferred from Electronic Annotation more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within cell redox homeostasis	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within cellular response to nitrogen starvation	IEP Inferred from Expression Pattern more info	PubMed
acts_upstream_of_or_within cellular response to phosphate starvation	IEP Inferred from Expression Pattern more info	PubMed
acts_upstream_of_or_within cellular response to sulfate starvation	IEP Inferred from Expression Pattern more info	PubMed
acts_upstream_of_or_within hydrogen peroxide catabolic process	NAS Non-traceable Author Statement more info
acts_upstream_of_or_within photoperiodism	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within response to cold	IEP Inferred from Expression Pattern more info	PubMed
acts_upstream_of_or_within response to light stimulus	IEP Inferred from Expression Pattern more info	PubMed
involved_in response to oxidative stress	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within response to oxidative stress	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in cytosol	HDA more info	PubMed
NOT located_in cytosol	RCA inferred from Reviewed Computational Analysis more info	PubMed
located_in cytosolic ribosome	HDA more info	PubMed
located_in mitochondrion	HDA more info	PubMed
located_in nucleus	ISM Inferred from Sequence Model more info
located_in peroxisome	HDA more info	PubMed
located_in peroxisome	NAS Non-traceable Author Statement more info
located_in plasma membrane	HDA more info	PubMed
located_in stromule	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: catalase 2

NP_001031791.1

catalase 2 (CAT2); FUNCTIONS IN: protein binding, catalase activity, cobalt ion binding; INVOLVED IN: in 10 processes; LOCATED IN: mitochondrion, cytosolic ribosome, stromule, peroxisome; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: Catalase-like domain, haem-dependent (InterPro:IPR020835), Catalase related subgroup (InterPro:IPR018028), Catalase (InterPro:IPR002226), Catalase, N-terminal (InterPro:IPR011614), Catalase-related immune responsive (InterPro:IPR010582); BEST Arabidopsis thaliana protein match is: catalase 1 (TAIR:AT1G20630.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

NP_195235.1

catalase 2 (CAT2); FUNCTIONS IN: protein binding, catalase activity, cobalt ion binding; INVOLVED IN: in 10 processes; LOCATED IN: mitochondrion, cytosolic ribosome, stromule, peroxisome, chloroplast; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: Catalase (InterPro:IPR002226), Catalase related subgroup (InterPro:IPR018028), Catalase-like domain, haem-dependent (InterPro:IPR020835), Catalase, N-terminal (InterPro:IPR011614), Catalase-related immune responsive (InterPro:IPR010582); BEST Arabidopsis thaliana protein match is: catalase 1 (TAIR:AT1G20630.1); Has 6114 Blast hits to 6094 proteins in 1849 species: Archae - 22; Bacteria - 4292; Metazoa - 675; Fungi - 546; Plants - 461; Viruses - 0; Other Eukaryotes - 118 (source: NCBI BLink).