POLLEN-EXPRESSED TRANSCRIPTION FACTOR 2 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Full Name: POLLEN-EXPRESSED TRANSCRIPTION FACTOR 2
Primary source: TAIR:AT4G35540
Locus tag: AT4G35540
See related: Araport:AT4G35540
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: F8D20.50; F8D20_50; Pollen-expressed Transcription Factor 2; PTF2
Summary: Encodes a novel plant-specific TFIIB-related protein that can interact with TBP2 and bind DNA. It can also form a homodimer and interact with the subunits of RNA polymerases. Mutant pollen fails to germinate.
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Genomic context

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See in Genome Data Viewer

Location:: chromosome: 4

Exon count:: 1

Sequence:: Chromosome: 4; NC_003075.7 (16873835..16875598)

Chromosome 4 - NC_003075.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

results suggest that PTF2(At4g35540) plays crucial roles in pollen germination and embryogenesis in Arabidopsis
Title: Pollen-expressed transcription factor 2 encodes a novel plant-specific TFIIB-related protein that is required for pollen germination and embryogenesis in Arabidopsis.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_119719.2

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables RNA polymerase binding	IDA Inferred from Direct Assay more info	PubMed
enables TFIIB-class transcription factor binding	IDA Inferred from Direct Assay more info	PubMed
enables double-stranded DNA binding	IDA Inferred from Direct Assay more info	PubMed
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein homodimerization activity	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within embryo development ending in seed dormancy	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within pollen germination	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	ISM Inferred from Sequence Model more info

General protein information

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Preferred Names: POLLEN-EXPRESSED TRANSCRIPTION FACTOR 2

NP_195279.1

zinc ion binding;transcription regulators; FUNCTIONS IN: transcription regulator activity, zinc ion binding; INVOLVED IN: regulation of transcription, DNA-dependent, regulation of transcription, transcription initiation; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Transcription factor TFIIB related (InterPro:IPR000812), Cyclin-like (InterPro:IPR011028), Zinc finger, TFIIB-type (InterPro:IPR013137); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

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Reference assembly

Genomic

NC_003075.7 Reference assembly

Range

16873835..16875598

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_119719.2 → NP_195279.1 POLLEN-EXPRESSED TRANSCRIPTION FACTOR 2 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_195279.1

Status: REVIEWED

UniProtKB/Swiss-Prot

O81787

UniProtKB/TrEMBL

A0A178US01, A0A5S9XZA1, A0A654FVU6

Conserved Domains (2) summary

COG1405
Location:1 → 257

SUA7; Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB [Transcription]

pfam08271
Location:1 → 35

TF_Zn_Ribbon; TFIIB zinc-binding