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    RABA4B RAB GTPase homolog A4B [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 830160, updated on 18-Sep-2024

    Summary

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    Official Symbol
    RABA4B
    Official Full Name
    RAB GTPase homolog A4B
    Primary source
    TAIR:AT4G39990
    Locus tag
    AT4G39990
    See related
    Araport:AT4G39990
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA RAB GTPASE HOMOLOG A 4B; ATGB3; ATRAB11G; ATRABA4B; GTP-BINDING PROTEIN 3; RAB GTPase homolog A4B; T5J17.160; T5J17_160
    Summary
    GTP-binding protein ATGB3
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    Genomic context

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    See RABA4B in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    2
    Sequence:
    Chromosome: 4; NC_003075.7 (18542551..18543978)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase 1 Neighboring gene tRNA-Ile Neighboring gene ncRNA Neighboring gene S-adenosyl-L-methionine-dependent methyltransferases superfamily protein Neighboring gene SNF1-related protein kinase 2.7 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Arabidopsis Rab GTPase RabA4b localizes to the tips of growing root hair cells. Preuss ML, et al. Plant Cell, 2004 Jun. PMID 15155878, Free PMC Article
    2. Electron tomography of RabA4b- and PI-4Kβ1-labeled trans Golgi network compartments in Arabidopsis. Kang BH, et al. Traffic, 2011 Mar. PMID 21134079
    3. Recruitment of PLANT U-BOX13 and the PI4Kβ1/β2 phosphatidylinositol-4 kinases by the small GTPase RabA4B plays important roles during salicylic acid-mediated plant defense signaling in Arabidopsis. Antignani V, et al. Plant Cell, 2015 Jan. PMID 25634989, Free PMC Article
    4. Myosin XIK of Arabidopsis thaliana accumulates at the root hair tip and is required for fast root hair growth. Park E, et al. PLoS One, 2013. PMID 24116145, Free PMC Article
    5. Interdependence of endomembrane trafficking and actin dynamics during polarized growth of Arabidopsis pollen tubes. Zhang Y, et al. Plant Physiol, 2010 Apr. PMID 20181757, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Involved in determining the composition of the cell wall, particularly with respect to hemicellulose content, possibly through regulating trafficking of hemicellulose from the Golgi to the apoplast. [RABA4b]
      Title: Null mutants of individual RABA genes impact the proportion of different cell wall components in stem tissue of Arabidopsis thaliana.
    2. RabA4b and PI-4Kbeta1 localize to budding secretory vesicles (SVs) in the trans Golgi network and to SVs en route to the cell surface.
      Title: Electron tomography of RabA4b- and PI-4Kβ1-labeled trans Golgi network compartments in Arabidopsis.
    3. RabA4b regulates membrane trafficking through a compartment involved in the polarized secretion of cell wall components in plant cells. [RabA4b]
      Title: The Arabidopsis Rab GTPase RabA4b localizes to the tips of growing root hair cells.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_120163.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables kinase binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell wall biogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within endocytic recycling IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in early endosome membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane HDA PubMed 
    located_in pollen tube tip IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in root hair tip IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in trans-Golgi network membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    RAB GTPase homolog A4B
    NP_195709.1
    • RAB GTPase homolog A4B (RABA4B); FUNCTIONS IN: GTP binding; INVOLVED IN: endocytic recycling; LOCATED IN: plasma membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Ras GTPase (InterPro:IPR001806), Small GTP-binding protein (InterPro:IPR005225), Small GTPase (InterPro:IPR020851), Ras (InterPro:IPR013753), Ras small GTPase, Rab type (InterPro:IPR003579), Rab11-related (InterPro:IPR015595); BEST Arabidopsis thaliana protein match is: RAB GTPase homolog A4A (TAIR:AT5G65270.1); Has 29206 Blast hits to 29157 proteins in 775 species: Archae - 30; Bacteria - 156; Metazoa - 15160; Fungi - 4303; Plants - 3469; Viruses - 20; Other Eukaryotes - 6068 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      18542551..18543978
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_120163.4 → NP_195709.1  RAB GTPase homolog A4B [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_195709.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q38923, Q8L958, Q9SMQ6
      UniProtKB/TrEMBL
      A0A178V216
      Conserved Domains (2) summary
      PLN03110
      Location:15 → 223
      PLN03110; Rab GTPase; Provisional
      cd01868
      Location:15 → 179
      Rab11_like; Rab GTPase family 11 (Rab11)-like includes Rab11a, Rab11b, and Rab25
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SMQ6.1

    Gene LinkOut

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