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    RPN8A RP non-ATPase subunit 8A [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 830463, updated on 18-Sep-2024

    Summary

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    Official Symbol
    RPN8A
    Official Full Name
    RP non-ATPase subunit 8A
    Primary source
    TAIR:AT5G05780
    Locus tag
    AT5G05780
    See related
    Araport:AT5G05780
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AE3; ASYMMETRIC LEAVES ENHANCER 3; ATHMOV34; MJJ3.19; MJJ3_19; PUTATIVE 26S PROTEASOME SUBUNIT ATHMOV34; RP non-ATPase subunit 8A
    Summary
    Encodes a putative 26S proteasome subunit RPN8a. The function of RPN8a and other 26S subunits may be required for specifying leaf adaxial identity.
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    Genomic context

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    See RPN8A in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    10
    Sequence:
    Chromosome: 5; NC_003076.8 (1735725..1738740)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene WUSCHEL related homeobox 7 Neighboring gene Duplicated homeodomain-like superfamily protein Neighboring gene tRNA-Arg

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The proteolytic function of the Arabidopsis 26S proteasome is required for specifying leaf adaxial identity. Huang W, et al. Plant Cell, 2006 Oct. PMID 17028202, Free PMC Article
    2. RPN1a, a 26S proteasome subunit, is required for innate immunity in Arabidopsis. Yao C, et al. Plant J, 2012 Sep. PMID 22577987
    3. Structure and functional analysis of the 26S proteasome subunits from plants. Fu H, et al. Mol Biol Rep, 1999 Apr. PMID 10363660
    4. Affinity purification of the Arabidopsis 26 S proteasome reveals a diverse array of plant proteolytic complexes. Book AJ, et al. J Biol Chem, 2010 Aug 13. PMID 20516081, Free PMC Article
    5. Proteomic analysis of the 26S proteasome reveals its direct interaction with transit peptides of plastid protein precursors for their degradation. Sako K, et al. J Proteome Res, 2014 Jul 3. PMID 24846764

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001203304.1
    NM_120660.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables metallopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in innate immune response IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within leaf morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within ubiquitin-dependent protein catabolic process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane HDA PubMed 
    part_of proteasome complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of proteasome regulatory particle IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    RP non-ATPase subunit 8A
    NP_001190233.1
    • RP non-ATPase subunit 8A (RPN8A); FUNCTIONS IN: molecular_function unknown; INVOLVED IN: ubiquitin-dependent protein catabolic process, leaf morphogenesis; LOCATED IN: proteasome complex, proteasome regulatory particle, lid subcomplex; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Mov34/MPN/PAD-1 (InterPro:IPR000555); BEST Arabidopsis thaliana protein match is: Mov34/MPN/PAD-1 family protein (TAIR:AT3G11270.2).
    NP_196197.1
    • RP non-ATPase subunit 8A (RPN8A); CONTAINS InterPro DOMAIN/s: Mov34/MPN/PAD-1 (InterPro:IPR000555); BEST Arabidopsis thaliana protein match is: Mov34/MPN/PAD-1 family protein (TAIR:AT3G11270.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      1735725..1738740
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001203304.1 → NP_001190233.1  RP non-ATPase subunit 8A [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001190233.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4K0U3
      Conserved Domains (2) summary
      cd08062
      Location:15 → 292
      MPN_RPN7_8; Mpr1p, Pad1p N-terminal (MPN) domains without catalytic isopeptidase activity, found in 19S proteasomal subunits Rpn7 and Rpn8
      PLN03246
      Location:10 → 304
      PLN03246; 26S proteasome regulatory subunit; Provisional

    2. NM_120660.4 → NP_196197.1  RP non-ATPase subunit 8A [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_196197.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O24412, Q6EMB3
      UniProtKB/TrEMBL
      A0A5S9Y2A3, A0A654FYV3
      Conserved Domains (1) summary
      PLN03246
      Location:10 → 307
      PLN03246; 26S proteasome regulatory subunit; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O24412.1

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