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    SSP5 SCP1-like small phosphatase 5 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 831059, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SSP5
    Official Full Name
    SCP1-like small phosphatase 5
    Primary source
    TAIR:AT5G11860
    Locus tag
    AT5G11860
    See related
    Araport:AT5G11860
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F14F18.30; F14F18_30; SCP1-like small phosphatase 5
    Summary
    Encodes a SCP1-like small phosphatase (SSP). Three SSPs form a unique group with long N-terminal extensions: AT5G46410 (SSP4), AT5G11860 (SSP5), AT4G18140 (SSP4b). SSP4 and SSP4b were localized exclusively in the nuclei, whereas SSP5 accumulated in both nuclei and cytoplasm. All three SSPs encodes active CTD phosphatases like animal SCP1 family proteins, with distinct substrate specificities: SSP4 and SSP4b could dephosphorylate both Ser2-PO(4) and Ser5-PO(4) of CTD, whereas SSP5 dephosphorylated only Ser5-PO(4).
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    Genomic context

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    See SSP5 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    6
    Sequence:
    Chromosome: 5; NC_003076.8 (3821733..3824298, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene YCF36, putative (DUF1230) Neighboring gene Protein kinase superfamily protein Neighboring gene Alkaline phytoceramidase (aPHC) Neighboring gene Pyridoxal-dependent decarboxylase family protein Neighboring gene harpin-induced protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis SCP1-like small phosphatases differentially dephosphorylate RNA polymerase II C-terminal domain. Feng Y, et al. Biochem Biophys Res Commun, 2010 Jun 25. PMID 20513350
    2. Inactivation of the CTD phosphatase-like gene OsCPL1 enhances the development of the abscission layer and seed shattering in rice. Ji H, et al. Plant J, 2010 Jan. PMID 19807881
    3. Molecular dissection of plant cytokinesis and phragmoplast structure: a survey of GFP-tagged proteins. Van Damme D, et al. Plant J, 2004 Nov. PMID 15469496
    4. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    NM_001085103.1
    NM_001343218.1
    NM_121224.4
    NM_180478.1
    NM_203038.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables RNA polymerase II CTD heptapeptide repeat phosphatase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within protein dephosphorylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chromosome HDA PubMed 
    located_in chromosome, centromeric region HDA PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus HDA PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    SCP1-like small phosphatase 5
    NP_001078572.1
    • SCP1-like small phosphatase 5; CONTAINS InterPro DOMAIN/s: Dullard-like phosphatase domain (InterPro:IPR011948), NLI interacting factor (InterPro:IPR004274); BEST Arabidopsis thaliana protein match is: SCP1-like small phosphatase 4 (TAIR:AT5G46410.1); Has 2780 Blast hits to 2771 proteins in 250 species: Archae - 0; Bacteria - 14; Metazoa - 839; Fungi - 559; Plants - 525; Viruses - 1; Other Eukaryotes - 842 (source: NCBI BLink).
    NP_001318546.1
    • SCP1-like small phosphatase 5; CONTAINS InterPro DOMAIN/s: Dullard-like phosphatase domain (InterPro:IPR011948), NLI interacting factor (InterPro:IPR004274); BEST Arabidopsis thaliana protein match is: SCP1-like small phosphatase 4 (TAIR:AT5G46410.1); Has 2780 Blast hits to 2771 proteins in 250 species: Archae - 0; Bacteria - 14; Metazoa - 839; Fungi - 559; Plants - 525; Viruses - 1; Other Eukaryotes - 842 (source: NCBI BLink).
    NP_196747.1
    • SCP1-like small phosphatase 5 (SSP5); CONTAINS InterPro DOMAIN/s: Dullard-like phosphatase domain (InterPro:IPR011948), NLI interacting factor (InterPro:IPR004274); BEST Arabidopsis thaliana protein match is: SCP1-like small phosphatase 4 (TAIR:AT5G46410.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).
    NP_974767.1
    • SCP1-like small phosphatase 5; CONTAINS InterPro DOMAIN/s: Dullard-like phosphatase domain (InterPro:IPR011948), NLI interacting factor (InterPro:IPR004274); BEST Arabidopsis thaliana protein match is: SCP1-like small phosphatase 4 (TAIR:AT5G46410.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      3821733..3824298 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_203038.3 → NP_974767.1  SCP1-like small phosphatase 5 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_974767.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UAZ5, A0A654G0C0, Q9LYI7
      Conserved Domains (1) summary
      pfam03031
      Location:114 → 273
      NIF; NLI interacting factor-like phosphatase

    2. NM_121224.4 → NP_196747.1  SCP1-like small phosphatase 5 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_196747.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UAZ5, A0A654G0C0, Q9LYI7
      Conserved Domains (1) summary
      pfam03031
      Location:114 → 273
      NIF; NLI interacting factor-like phosphatase

    3. NM_001343218.1 → NP_001318546.1  SCP1-like small phosphatase 5 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UAZ5, A0A654G0C0, Q9LYI7
      Conserved Domains (1) summary
      pfam03031
      Location:114 → 273
      NIF; NLI interacting factor-like phosphatase

    4. NM_180478.1 → NP_850809.1  SCP1-like small phosphatase 5 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_850809.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UAZ5, A0A654G0C0, Q9LYI7
      Conserved Domains (1) summary
      pfam03031
      Location:114 → 273
      NIF; NLI interacting factor-like phosphatase

    5. NM_001085103.1 → NP_001078572.1  SCP1-like small phosphatase 5 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001078572.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UAZ5, A0A654G0C0, Q9LYI7
      Conserved Domains (1) summary
      pfam03031
      Location:114 → 273
      NIF; NLI interacting factor-like phosphatase
    Nucleotide Protein
    Heading Accession and Version

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