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    2-aminoethanethiol dioxygenase, putative (DUF1637) [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 833986, updated on 18-Sep-2024

    Summary

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    Official Full Name
    2-aminoethanethiol dioxygenase, putative (DUF1637)
    Primary source
    TAIR:AT5G39890
    Locus tag
    AT5G39890
    See related
    Araport:AT5G39890
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    MYH19.8; MYH19_8; PCO2; plant cysteine oxidase 2
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    Genomic context

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    Location:
    chromosome: 5
    Exon count:
    5
    Sequence:
    Chromosome: 5; NC_003076.8 (15974270..15976270)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene hypothetical protein (DUF1216) Neighboring gene uncharacterized protein Neighboring gene tRNA-Ala Neighboring gene Small GTP-binding protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Plant cysteine oxidases control the oxygen-dependent branch of the N-end-rule pathway. Weits DA, et al. Nat Commun, 2014 Mar 6. PMID 24599061, Free PMC Article
    2. Molecular basis for cysteine oxidation by plant cysteine oxidases from Arabidopsis thaliana. Chen Z, et al. J Struct Biol, 2021 Mar. PMID 33207269
    3. Integrative Analysis from the Epigenome to Translatome Uncovers Patterns of Dominant Nuclear Regulation during Transient Stress. Lee TA, et al. Plant Cell, 2019 Nov. PMID 31519798, Free PMC Article
    4. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Data indicate that cysteine oxidases PCO1 (At5g15120) and PCO2 (At5g39890) are hypoxia-inducible genes.
      Title: Plant cysteine oxidases control the oxygen-dependent branch of the N-end-rule pathway.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    NM_001344309.1
    NM_123352.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables cysteine dioxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables iron ion binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cellular response to hypoxia HEP PubMed 
    acts_upstream_of_or_within detection of hypoxia IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within peptidyl-cysteine oxidation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within response to hypoxia IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    2-aminoethanethiol dioxygenase, putative (DUF1637)
    NP_198805.1
    • Protein of unknown function (DUF1637); FUNCTIONS IN: cysteamine dioxygenase activity; INVOLVED IN: oxidation reduction; LOCATED IN: cellular_component unknown; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF1637 (InterPro:IPR012864); BEST Arabidopsis thaliana protein match is: Protein of unknown function (DUF1637) (TAIR:AT5G15120.1); Has 361 Blast hits to 361 proteins in 93 species: Archae - 0; Bacteria - 0; Metazoa - 102; Fungi - 0; Plants - 224; Viruses - 0; Other Eukaryotes - 35 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      15974270..15976270
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_123352.3 → NP_198805.1  2-aminoethanethiol dioxygenase, putative (DUF1637) [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_198805.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8LGJ5, Q9FLE5
      UniProtKB/TrEMBL
      A0A5S9Y9F2, A0A654G6G3, A0A7G2FCG9
      Conserved Domains (1) summary
      pfam07847
      Location:78 → 274
      PCO_ADO

    2. NM_001344309.1 → NP_001330989.1  2-aminoethanethiol dioxygenase, putative (DUF1637) [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BCH5, A0A7G2FCG9
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8LGJ5.1

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